With the resurgence of electrosynthesis in organic chemistry, there is a significant increase
in the number of routes available for late-stage functionalization (LSF) of drugs …

This review summarizes examples of organic electrosynthesis from the peer-reviewed
literature from 2000 to 2023 that have been conducted on scales of 20 g or above. A …

Herein, we demonstrate the ability of isonitriles to be used as alkyl radical precursors in a
photoredox-catalyzed transformation involving selective C–N cleavage and Csp3–Csp2 …

Cross-electrophile coupling has emerged as an attractive and efficient method for the
synthesis of C (sp2)–C (sp3) bonds. These reactions are most often catalyzed by nickel …

A strategy for transition metal‐free cross‐coupling of alkyl nitroso‐carbamates and boronic
acids is reported. The N‐nitroso carbamates are easily prepared from the corresponding …

Medicinal plants have been used as homeopathic and natural remedies for various ailments
throughout history. Although modern medicine and drug discovery have made huge …

Although screening technology has heavily impacted the fields of metal catalysis and drug
discovery, its application to the discovery of new catalyst classes has been limited. The …

Herein, we report the first allenylic alkylation with bench-stable aliphatic amine-derived
Katritzky salts via photoredox/nickel dual-catalyzed reductive deaminative cross-electrophile …

An environmentally benign electrochemical approach has been developed for the
construction of β-sulfonylated BODIPYs by using sulfonylhydrazide as the sulfonyl source …

Etherification and amination of aryl halide scaffolds are commonly used reactions in parallel
medicinal chemistry to rapidly scan structure–activity relationships with abundant building …