Background Traditionally, renal function in critically ill patients has been assessed to identify
renal dysfunction, and dose adjustment is generally accepted in such a context …

Augmented renal clearance (ARC) is a manifestation of enhanced renal function seen in
critically ill patients. The use of regular unadjusted doses of renally eliminated drugs in …

Augmented renal clearance (ARC) has been reported in approximately 30–65% of patients
in the intensive care unit (ICU) despite the presence of a normal serum creatinine …

Highlights•Augmented renal clearance (ARC) is a prevalent condition in the critically
ill.•ARC may result in sub-therapeutic exposure of renally eliminated antibiotics.•Beta …

Despite the wide clinical use of vancomycin, controversy remains regarding its optimal
dosage regimens. This can be attributed to the large between-and within-subject variability …

Kidney function assessment in the critically ill overlooks the possibility for hyperfunctioning
kidneys, known as augmented renal clearance (ARC), which could contribute to therapeutic …

Many critically ill patients display a supraphysiological renal function with enhanced renal
perfusion and glomerular hyperfiltration. This phenomenon described as augmented renal …

Background Augmented renal clearance (ARC) remains poorly evaluated in ICU. The
objective of this study is to provide a full description of ARC in ICU including prevalence …

Background Appropriate utilization of vancomycin is important to attain therapeutic targets
while avoiding clinical failure and the development of antimicrobial resistance. Our aim was …

Objectives: Augmented renal clearance (ARC) is a state of enhanced renal function
commonly observed in 30%–65% of critically ill patients despite normal serum creatinine …