Hyperglycaemia that develops during pregnancy and resolves after birth has been
recognized for over 50 years, but uniform worldwide consensus is lacking about threshold …

Epigenetic mechanisms control gene activity and the development of an organism. The
epigenome includes DNA methylation, histone modifications, and RNA-mediated processes …

Gestational diabetes, the most common medical disorder in pregnancy, is defined as
glucose intolerance resulting in hyperglycaemia that begins or is first diagnosed in …

Insulin resistance changes over time during pregnancy, and in the last half of the pregnancy,
insulin resistance increases considerably and can become severe, especially in women with …

Gestational diabetes mellitus (GDM) is the most common metabolic complication of
pregnancy, with a prevalence that has increased significantly in the last decade, coming to …

The type 2 diabetes epidemic and one of its predisposing factors, obesity, are major
influences on global health and economic burden. It is accepted that genetics and the …

Fetal metabolic programming caused by the adverse intrauterine environment can induce
metabolic syndrome in adult offspring. Adverse intrauterine environment introduces fetal …

Background Higher maternal plasma glucose (PG) concentrations, even below gestational
diabetes mellitus (GDM) thresholds, are associated with adverse offspring outcomes, with …

Overweight and obesity during pregnancy have been associated with increased birth
weight, childhood obesity, and noncommunicable diseases in the offspring, leading to a …

Nutrition is a modifiable key factor that is able to interact with both the genome and
epigenome to influence human health and fertility. In particular, specific genetic variants can …