Therapy resistance is a characteristic of cancer cells that significantly reduces the
effectiveness of drugs. Despite the popularity of cisplatin (CP) as a chemotherapeutic agent …

Cancer is one of the leading causes of death worldwide. Conventional therapies, including
surgery, radiation, and chemotherapy have achieved increased survival rates for many types …

Abstract In recent years, 5-methylcytosine (m5C) RNA modification has emerged as a key
player in regulating RNA metabolism and function through coding as well as non-coding …

Diacylglycerol (DAG) is a lipid second messenger that is generated in response to
extracellular stimuli and channels intracellular signals that affect mammalian cell …

Simple Summary Estrogen is known to drive the growth of estrogen-receptor-positive breast
cancers, the most common breast cancer subtype. Drugs that target the estrogen receptor by …

Sinapic acid is a hydroxycinnamic acid widespread in the plant kingdom, known to be a
potent anti-oxidant used for the treatment of cancer, infections, oxidative stress, and …

Protein kinase C α (PKCα) is a ubiquitously expressed member of the PKC family of
serine/threonine kinases with diverse functions in normal and neoplastic cells. Early studies …

Triple‑negative breast cancer (TNBC) is a specific type of breast cancer with poor overall
survival (OS) time. Previous studies revealed that microRNAs (miRNAs/miRs) serve …

It has been proposed that cancer stem cells (CSCs) are responsible for almost all malignant
phenotypes of tumors. Long non-coding RNA WT1 antisense RNA (WT1-AS) has been …

Simple Summary Protein kinase C (PKC) isozymes play key roles in the proliferation,
differentiation, survival, migration, invasion, apoptosis, and anticancer drug resistance of …