Mendelian randomization (MR) is a term that applies to the use of genetic variation to
address causal questions about how modifiable exposures influence different outcomes …

Mendelian randomization (MR) is a method of studying the causal effects of modifiable
exposures (ie, potential risk factors) on health, social, and economic outcomes using genetic …

Humans vary substantially in their willingness to take risks. In a combined sample of over 1
million individuals, we conducted genome-wide association studies (GWAS) of general risk …

Intelligence—the ability to learn, reason and solve problems—is at the forefront of
behavioural genetic research. Intelligence is highly heritable and predicts important …

Little is known about the genetic architecture of traits affecting educational attainment other
than cognitive ability. We used genomic structural equation modeling and prior genome …

Socioeconomic differences in behaviour are pervasive and well documented, but their
causes are not yet well understood. Here, we make the case that a cluster of behaviours is …

Polygenic scores are a popular tool for prediction of complex traits. However, prediction
estimates in samples of unrelated participants can include effects of population stratification …

Social science genetics is concerned with understanding whether, how and why genetic
differences between human beings are linked to differences in behaviours and …

Individual differences in human intelligence, as assessed using cognitive test scores, have a
well-replicated, hierarchical phenotypic covariance structure. They are substantially stable …

Human DNA polymorphisms vary across geographic regions, with the most commonly
observed variation reflecting distant ancestry differences. Here we investigate the …