The capsule of Cryptococcus neoformans is its dominant virulence factor and plays a key
role in the biology of this fungus. In this essay, we focus on the capsule as a cellular …

The usage of fluconazole and amphotericin B in clinical settings is often limited by, among
other things, drug resistance development and undesired side effects. Thus, there is a …

The social amoeba Dictyostelium discoideum is a well-established model organism to study
the interaction between bacteria and phagocytes. In contrast, research using D. discoideum …

Among the best-studied interactions between soil phagocytic predators and a human-
pathogenic fungus is that of Acanthamoeba castellanii and Cryptococcus neoformans. The …

We previously reported that 3-hydroxy fatty acids promoted the survival of cryptococcal cells
when acted upon by amoebae. To expand on this, the current study sought to explain how …

Photodynamic treatment (PDT) is often successful when used against aerobic microbes,
given their natural susceptibility to oxidative damage. To this end, the current study aimed to …

Despite the ubiquitous distribution of oxylipins in plants, animals, and microbes, and the
application of numerous analytical techniques to study these molecules, 3-OH oxylipins …

Spoilage and mycotoxin production by mycelial fungi threatens global food security. Climate
change and increasingly complex food value chains may exacerbate these concerns …

Lipids play important roles in living systems as they serve as building blocks of cell plasma
membranes, 1 energy deposits, 2 and signaling molecules. 3, 4 Unsaturated lipids, which …

To simulate Cryptococcus infection, amoeba, which is the natural predator of cryptococcal
cells in the environment, can be used as a model for macrophages. This predatory …