Flaxseed lignans as important dietary polyphenols for cancer prevention and treatment: Chemistry, pharmacokinetics, and molecular targets
SF De Silva, J Alcorn - Pharmaceuticals, 2019 - mdpi.com
Cancer causes considerable morbidity and mortality across the world. Socioeconomic,
environmental, and lifestyle factors contribute to the increasing cancer prevalence …
environmental, and lifestyle factors contribute to the increasing cancer prevalence …
Natural polyphenols for drug delivery and tissue engineering construction: A review
Y Liu, Y Shi, M Zhang, F Han, W Liao, X Duan - European Journal of …, 2024 - Elsevier
Polyphenols, natural compounds rich in phenolic structures, are gaining prominence due to
their antioxidant, anti-inflammatory, antibacterial, and anticancer properties, making them …
their antioxidant, anti-inflammatory, antibacterial, and anticancer properties, making them …
Treatment with flaxseed oil induces apoptosis in cultured malignant cells
AL Buckner, CA Buckner, S Montaut, RM Lafrenie - Heliyon, 2019 - cell.com
Flaxseed oil is widely recognized for its exceptional nutritional value, high concentration of
fiber-based lignans and large amounts of ω-fatty acids. It is one of a generic group of …
fiber-based lignans and large amounts of ω-fatty acids. It is one of a generic group of …
Effect of dietary flaxseed intake on circulating sex hormone levels among postmenopausal women: a randomized controlled intervention trial
VC Chang, M Cotterchio, BA Boucher… - Nutrition and …, 2019 - Taylor & Francis
Lignan intake, and its richest food source, flaxseed, have been associated with reduced
breast cancer risk. Endogenous sex hormones, such as estrogens, play a role in breast …
breast cancer risk. Endogenous sex hormones, such as estrogens, play a role in breast …
Pro-apoptotic and anti-angiogenic actions of 2-methoxyestradiol and docosahexaenoic acid, the biologically derived active compounds from flaxseed diet, in …
Background We have previously shown that a whole flaxseed supplemented diet decreased
the onset and severity of ovarian cancer in the laying hen, the only known animal model of …
the onset and severity of ovarian cancer in the laying hen, the only known animal model of …
Enterolactone has stronger effects than enterodiol on ovarian cancer
H Liu, J Liu, S Wang, Z Zeng, T Li, Y Liu… - Journal of ovarian …, 2017 - Springer
Background Ovarian cancer is one of the three leading gynecological malignancies,
characterized by insidious growth, highly frequent metastasis, and quick development of …
characterized by insidious growth, highly frequent metastasis, and quick development of …
Flaxseed and its components differentially affect estrogen targets in pre-neoplastic hen ovaries
A Dikshit, C Gao, C Small, K Hales, DB Hales - The Journal of steroid …, 2016 - Elsevier
Flaxseed has been studied for decades for its health benefits that include anti-cancer, cardio-
protective, anti-diabetic, anti-inflammatory properties. The biologically active components …
protective, anti-diabetic, anti-inflammatory properties. The biologically active components …
Performance and egg quality of laying hens fed flaxseed: Highlights on n-3 fatty acids, cholesterol, lignans and isoflavones
S Mattioli, S Ruggeri, B Sebastiani, G Brecchia… - Animal, 2017 - cambridge.org
Flaxseed is a rich source of α-linolenic acid and phytoestrogens, mainly lignans, whose
metabolites (enterodiol and enterolactone) can affect estrogen functions. The present study …
metabolites (enterodiol and enterolactone) can affect estrogen functions. The present study …
Influence of flaxseed (Linum usitatissimum) on female reproduction
AV Sirotkin - Planta Medica, 2023 - thieme-connect.com
This review describes the chemical composition of flaxseed (Linum usitatissimum) and its
general health effects, as well as the currently available knowledge concerning its action on …
general health effects, as well as the currently available knowledge concerning its action on …
Ovary transcriptomic analysis reveals regulation effects of dietary fish oil on hormone, lipid, and glucose metabolism in female adult spotted scat (Scatophagus argus)
T Wang, ZL Liu, GL Li, UF Mustapha… - Frontiers in Marine …, 2022 - frontiersin.org
In the aquaculture industry, fish oil is widely used as a nutritional supplement to promote the
gonadal maturation of broodstocks, while the mechanism of fish oil on ovary development …
gonadal maturation of broodstocks, while the mechanism of fish oil on ovary development …