Intact, coordinated, and precisely regulated cerebrovascular responses are required for the
maintenance of cerebral metabolic homeostasis, adequate perfusion, oxygen delivery, and …

Abstract Simonson, Tatum S. Altitude adaptation: A glimpse through various lenses. High Alt
Med Biol 16: 125–137, 2015.—Recent availability of genome-wide data from highland …

COVID-19 hinders oxygen transport to the consuming tissues by at least two mechanisms: In
the injured lung, saturation of hemoglobin is compromised, and in the tissues, an associated …

Living, working and exercising in extreme terrestrial environments are challenging tasks
even for healthy humans of the modern new age. The issue is not just survival in remote …

BACKGROUND: An intriguing potential clinical use of cerebral oximeter measurements (S ct
O 2) is the ability to noninvasively estimate jugular bulb venous oxygen saturation (S jv O 2) …

Cerebrovascular reactivity can be measured as the cerebrovascular flow response to a
hypercapnic challenge. The many faceted responses of cerebral blood flow to combinations …

The assessment of resting perfusion measures (mean transit time, cerebral blood flow, and
cerebral blood volume) with magnetic resonance imaging currently requires the presence of …

Objective: High altitude is characterized by low oxygen pressure, resulting in multiple
adaptive responses. Tibetans who have lived in the plateau for thousands of years have …

Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in
neurovascular coupling. NO produced by neurons diffuses into the smooth muscle …

Key points The control of cerebral blood flow in hypoxia, anaemia and hypocapnia is
reviewed with an emphasis on the links between cerebral blood flow and possible stimuli. A …