Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is
overexpressed in many epithelial malignancies and correlates with cancer progression …

The role of mesenchymal stromal cells (MSCs) in the tumor microenvironment is well
described. Available data support that MSCs display anticancer activities, and that their …

Proton pump inhibitors (PPIs) are administered commonly to aged people; however, their
effect on colorectal cancer (CRC) has still not been fully elucidated. Here, we examined the …

Tight junction (TJ) protein cingulin (CGN) and transcription factor forkhead box protein O1
(FOXO1) contribute to the development of various cancers. Histone deacetylase (HDAC) …

Objective: We aimed to explore the relationship between peripheral blood circulating tumor
cells (CTCs) and the expression of Claudin-4 in patients with breast cancer, and further …

Aims: To identify the clinical roles of CLDN10 in clear cell renal cell carcinoma (ccRCC).
Materials&methods: Using data from TCGA-KIRC, GEO DataSets and laboratory …

Budding at the tumor invasive front has been correlated with the malignant properties of
many cancers. Malic enzyme 1 (ME1) promotes the Warburg effect in cancer cells and …

Claudin-4 (CLDN4) is a tight junction protein to maintain the cancer microenvironment. We
recently reported the role of the CLDN4 not forming tight junction in the induction of …

Claudin‑4, a member of the claudin multigene family, participates in events associated with
mesenchymal‑like activity of cancerous cells. Claudin‑4 expression is upregulated in …

Studies have found that C‑C motif chemokine ligand 20 (CCL20)/C‑C motif chemokine
receptor 6 (CCR6)/notch receptor 1 (Notch1) signaling serves an important role in various …