Click chemistry strategies for the accelerated synthesis of functional macromolecules
Click chemistry is one of the most powerful strategies for constructing polymeric soft
materials with precise control over architecture and functionality. In this review, we provide a …
materials with precise control over architecture and functionality. In this review, we provide a …
Dynamic covalent hydrogels as biomaterials to mimic the viscoelasticity of soft tissues
S Tang, BM Richardson, KS Anseth - Progress in Materials Science, 2021 - Elsevier
The extracellular matrix (ECM) and its mechanical properties play an important role in
regulating the cellular responses that occur during tissue regeneration, wound healing, and …
regulating the cellular responses that occur during tissue regeneration, wound healing, and …
Chemical stimuli-induced reversible bond cleavage in covalently crosslinked hydrogels
Stimuli-responsive hydrogels are known as a new category of smart materials with
responsivity toward various stimulants. Controllable reversible bond dissociation and …
responsivity toward various stimulants. Controllable reversible bond dissociation and …
Hydrogels based on pH-responsive reversible carbon–nitrogen double-bond linkages for biomedical applications
Z Zhang, C He, X Chen - Materials Chemistry Frontiers, 2018 - pubs.rsc.org
Covalently-crosslinked hydrogels are formed due to the generation of new covalent
crosslinking bonds in situ, leading to the formation of covalently-linked networks. However …
crosslinking bonds in situ, leading to the formation of covalently-linked networks. However …
Dual dynamically crosslinked thermosensitive hydrogel with self-fixing as a postoperative anti-adhesion barrier
Z Li, L Liu, Y Chen - Acta biomaterialia, 2020 - Elsevier
Tissue adhesion is a severe postoperative complication. Various strategies have been
developed to minimize postoperative adhesion, but the clinical efficacy is still far from …
developed to minimize postoperative adhesion, but the clinical efficacy is still far from …
The emergence of oxime click chemistry and its utility in polymer science
The synthesis of new, highly functional and dynamic polymeric materials has risen
dramatically since the introduction of click chemistry in 2001. This diverse set of reactions …
dramatically since the introduction of click chemistry in 2001. This diverse set of reactions …
Preventing post-surgical cardiac adhesions with a catechol-functionalized oxime hydrogel
M Fujita, GM Policastro, A Burdick, HT Lam… - Nature …, 2021 - nature.com
Post-surgical cardiac adhesions represent a significant problem during routine
cardiothoracic procedures. This fibrous tissue can impair heart function and inhibit surgical …
cardiothoracic procedures. This fibrous tissue can impair heart function and inhibit surgical …
Doubly dynamic self‐healing materials based on oxime click chemistry and boronic acids
J Collins, M Nadgorny, Z Xiao… - Macromolecular rapid …, 2017 - Wiley Online Library
The dynamic covalent characteristics of oxime and boronate ester bonds have been
explored. A small excess of a competing aldehyde under acidic conditions resulted in oxime …
explored. A small excess of a competing aldehyde under acidic conditions resulted in oxime …
Click-functionalized hydrogel design for mechanobiology investigations
The advancement of click-functionalized hydrogels in recent years has coincided with rapid
growth in the fields of mechanobiology, tissue engineering, and regenerative medicine …
growth in the fields of mechanobiology, tissue engineering, and regenerative medicine …
Strong poly (ethylene oxide) based gel adhesives via oxime cross-linking
There is a demand for materials to replace or augment the use of sutures and staples in
surgical procedures. Currently available commercial surgical adhesives provide either high …
surgical procedures. Currently available commercial surgical adhesives provide either high …