Regulation of Zbp1 by miR-99b-5p in microglia controls the development of schizophrenia-like symptoms in mice

L Kaurani, MR Islam, U Heilbronner, DM Krüger… - The EMBO …, 2024 - embopress.org
Current approaches to the treatment of schizophrenia have mainly focused on the protein-
coding part of the genome; in this context, the roles of microRNAs have received less …

Principales características fenotípicas crónico degenerativas asociadas al síndrome de Down: Una revisión narrativa

K Esparza-Ocampo… - Revista Médica de la …, 2023 - medigraphic.com
El síndrome de Down (SD) es la cromosomopatía más común, con una prevalencia de 3.7 y
2.9 por 10,000 nacimientos en México y Sinaloa, respectivamente. Aunque la esperanza de …

[HTML][HTML] Down Syndrome in Children: A Primary Immunodeficiency with Immune Dysregulation

A Szczawińska-Popłonyk, N Popłonyk, K Awdi - Children, 2024 - mdpi.com
Background: The multisystemic features of Down syndrome (DS) in children are
accompanied by immunodeficiency, making them susceptible to infections and immune …

Competing Endogenous RNAs Crosstalk in Hippocampus: A Potential Mechanism for Neuronal Developing Defects in Down Syndrome

H Zhao, G Lou, Y Shao, T Wang, H Wang… - Journal of Molecular …, 2024 - Springer
Down syndrome (DS) is the most example of aneuploidy, resulting from an additional copy
of all or part of chromosome 21. Competing endogenous RNAs (ceRNAs) play important …

A novel miR-99b-5p-Zbp1 pathway in microglia contributes to the pathogenesis of schizophrenia

L Kaurani, MR Islam, U Heilbronner, DM Krüger… - bioRxiv, 2023 - biorxiv.org
Schizophrenia is a psychiatric disorder that is still not readily treatable. Pharmaceutical
advances in the treatment of schizophrenia have mainly focused on the protein coding part …

[PDF][PDF] Down Syndrome in Children: An Inborn Error of Immunity with Immune Dysregulation

A Szczawińska-Popłonyk, N Popłonyk, K Awdi - 2024 - preprints.org
Background. The multisystemic features of Down syndrome (DS) in children are
accompanied by an immunodeficiency, making them susceptible to infections and immune …

Predominant chronic degenerative phenotypic features associated with Down syndrome: A narrative review

K Esparza-Ocampo… - Revista Médica de la …, 2023 - medigraphic.com
Down syndrome (DS) is the most common chromosomopathy, with a prevalence of 3.7 and
2.9 per 10,000 births in Mexico and Sinaloa, respectively. Although life expectancy has been …