Overview of dual-acting drug methotrexate in different neurological diseases, autoimmune pathologies and cancers

P Koźmiński, PK Halik, R Chesori… - International journal of …, 2020 - mdpi.com
Methotrexate, a structural analogue of folic acid, is one of the most effective and extensively
used drugs for treating many kinds of cancer or severe and resistant forms of autoimmune …

Diagnosis and treatment of primary CNS lymphoma in immunocompetent patients: guidelines from the European Association for Neuro-Oncology

K Hoang-Xuan, E Bessell, J Bromberg… - The Lancet …, 2015 - thelancet.com
The management of primary CNS lymphoma is one of the most controversial topics in neuro-
oncology because of the complexity of the disease and the very few controlled studies …

European Association of Neuro-Oncology (EANO) guidelines for treatment of primary central nervous system lymphoma (PCNSL)

K Hoang-Xuan, M Deckert, AJM Ferreri… - Neuro …, 2023 - academic.oup.com
The management of primary central nervous system (PCNSL) is one of the most
controversial topics in neuro-oncology because of the complexity of the disease and the …

Primary brain tumours in adults

D Ricard, A Idbaih, F Ducray, M Lahutte… - The Lancet, 2012 - thelancet.com
Important advances have been made in the understanding and management of adult
gliomas and primary CNS lymphomas—the two most common primary brain tumours …

Guidelines for the diagnosis and management of primary central nervous system diffuse large B‐cell lymphoma.

CP Fox, EH Phillips, J Smith, K Linton… - British journal of …, 2019 - search.ebscohost.com
The article offers guidelines for the diagnosis and management of primary central nervous
system diffuse large B-cell lymphoma. It informs on symptoms associated with the disease …

[HTML][HTML] First-line treatment and outcome of elderly patients with primary central nervous system lymphoma (PCNSL)—a systematic review and individual patient data …

B Kasenda, AJM Ferreri, E Marturano, D Forst… - Annals of …, 2015 - Elsevier
Background To investigate prognosis and effects of first-line therapy in elderly primary
central nervous system lymphoma (PCNSL) patients. Patients and methods A systematic …

Methotrexate and temozolomide versus methotrexate, procarbazine, vincristine, and cytarabine for primary CNS lymphoma in an elderly population: an intergroup …

A Omuro, O Chinot, L Taillandier… - The Lancet …, 2015 - thelancet.com
Background No standard chemotherapy regimen exists for primary CNS lymphoma,
reflecting an absence of randomised studies. We prospectively tested two promising …

Diagnosis and treatment of primary CNS lymphoma

A Korfel, U Schlegel - Nature Reviews Neurology, 2013 - nature.com
Primary CNS lymphoma (PCNSL) is a rare lymphoma that is confined to the CNS, with low
tendency for systemic dissemination and a relatively aggressive course. Outcome in patients …

Primary central nervous system lymphoma

ER Gerstner, TT Batchelor - Primary Central Nervous System Tumors …, 2011 - Springer
Non-Hodgkin lymphoma rarely presents as an extranodal lymphoma that is restricted to the
CNS known as primary CNS lymphoma (PCNSL). PCNSL can affect multiple parts of the …

High-dose methotrexate with or without rituximab in newly diagnosed primary CNS lymphoma

M Holdhoff, P Ambady, A Abdelaziz, G Sarai… - Neurology, 2014 - AAN Enterprises
Objective: To evaluate the efficacy of rituximab (R) when added to high-dose methotrexate
(HD-MTX) in patients with newly diagnosed immunocompetent primary CNS lymphomas …