The ECM‐cell interaction of cartilage extracellular matrix on chondrocytes
Y Gao, S Liu, J Huang, W Guo, J Chen… - BioMed research …, 2014 - Wiley Online Library
Cartilage extracellular matrix (ECM) is composed primarily of the network type II collagen
(COLII) and an interlocking mesh of fibrous proteins and proteoglycans (PGs), hyaluronic …
(COLII) and an interlocking mesh of fibrous proteins and proteoglycans (PGs), hyaluronic …
Filamins in cell signaling, transcription and organ development
AX Zhou, JH Hartwig, LM Akyürek - Trends in cell biology, 2010 - cell.com
Filamins are large actin-binding proteins that stabilize delicate three-dimensional actin
filament networks and link them to cellular membranes where they integrate cell …
filament networks and link them to cellular membranes where they integrate cell …
Genome-wide parallelism underlies contemporary adaptation in urban lizards
KM Winchell, SC Campbell-Staton… - Proceedings of the …, 2023 - National Acad Sciences
Urbanization drastically transforms landscapes, resulting in fragmentation, degradation, and
the loss of local biodiversity. Yet, urban environments also offer opportunities to observe …
the loss of local biodiversity. Yet, urban environments also offer opportunities to observe …
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
Large‐scale cancer genome sequencing has uncovered thousands of gene mutations, but
distinguishing tumor driver genes from functionally neutral passenger mutations is a major …
distinguishing tumor driver genes from functionally neutral passenger mutations is a major …
Filamins in mechanosensing and signaling
Z Razinia, T Mäkelä, J Ylänne… - Annual review of …, 2012 - annualreviews.org
Filamins are essential, evolutionarily conserved, modular, multidomain, actin-binding
proteins that organize the actin cytoskeleton and maintain extracellular matrix connections …
proteins that organize the actin cytoskeleton and maintain extracellular matrix connections …
[PDF][PDF] Matrix vesicles: structure, composition, formation and function in calcification
RE Wuthier, GF Lipscomb - Front Biosci, 2011 - article.imrpress.com
Introduction 3. Morphology of matrix vesicles (MVs) 3.1. Conventional transmission electron
microscopy 3.2. Cryofixation, freeze-substitution electron microscopy 3.3. Freeze-fracture …
microscopy 3.2. Cryofixation, freeze-substitution electron microscopy 3.3. Freeze-fracture …
High prevalence of growth plate gene variants in children with familial short stature treated with GH
L Plachy, V Strakova, L Elblova… - The Journal of …, 2019 - academic.oup.com
Context Familial short stature (FSS) is a term describing a growth disorder that is vertically
transmitted. Milder forms may result from the combined effect of multiple genes; more severe …
transmitted. Milder forms may result from the combined effect of multiple genes; more severe …
Filamin A regulates cardiovascular remodeling
S Bandaru, C Ala, AX Zhou, LM Akyürek - International journal of …, 2021 - mdpi.com
Filamin A (FLNA) is a large actin-binding cytoskeletal protein that is important for cell motility
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …
by stabilizing actin networks and integrating them with cell membranes. Interestingly, a C …
Genetics of osteoporosis: accelerating pace in gene identification and validation
Osteoporosis is characterized by low bone mineral density and structural deterioration of
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …
bone tissue, leading to an increased risk of fractures. It is the most common metabolic bone …
Rapamycin regulates autophagy and cell adhesion in induced pluripotent stem cells
A Sotthibundhu, K McDonagh… - Stem Cell Research & …, 2016 - Springer
Background Cellular reprogramming is a stressful process, which requires cells to engulf
somatic features and produce and maintain stemness machineries. Autophagy is a process …
somatic features and produce and maintain stemness machineries. Autophagy is a process …