[HTML][HTML] The SMN complex at the crossroad between RNA metabolism and neurodegeneration
In the cell, RNA exists and functions in a complex with RNA binding proteins (RBPs) that
regulate each step of the RNA life cycle from transcription to degradation. Central to this …
regulate each step of the RNA life cycle from transcription to degradation. Central to this …
[HTML][HTML] Function and dysfunction of GEMIN5: understanding a novel neurodevelopmental disorder
CH Nelson, UB Pandey - Neural Regeneration Research, 2024 - journals.lww.com
The recent identification of a neurodevelopmental disorder with cerebellar atrophy and
motor dysfunction (NEDCAM) has resulted in an increased interest in GEMIN5, a …
motor dysfunction (NEDCAM) has resulted in an increased interest in GEMIN5, a …
[HTML][HTML] Oligomerization regulates the interaction of Gemin5 with members of the SMN complex and the translation machinery
R Francisco-Velilla, S Abellan, A Embarc-Buh… - Cell Death …, 2024 - nature.com
RNA-binding proteins are multifunctional molecules impacting on multiple steps of gene
regulation. Gemin5 was initially identified as a member of the survival of motor neurons …
regulation. Gemin5 was initially identified as a member of the survival of motor neurons …
Enhancing cryo-EM structure prediction with DeepTracer and AlphaFold2 integration
Understanding the protein structures is invaluable in various biomedical applications, such
as vaccine development. Protein structure model building from experimental electron …
as vaccine development. Protein structure model building from experimental electron …
[HTML][HTML] Phosphorylation of T897 in the dimerization domain of Gemin5 modulates protein interactions and translation regulation
R Francisco-Velilla, A Embarc-Buh, S Abellan… - Computational and …, 2022 - Elsevier
Gemin5 is a multifunctional RNA binding protein (RBP) organized in domains with a
distinctive structural organization. The protein is a hub for several protein networks …
distinctive structural organization. The protein is a hub for several protein networks …
[HTML][HTML] 1-L Transcription of SARS-CoV-2 Spike Protein S1 Subunit
J Nahalka - International Journal of Molecular Sciences, 2024 - mdpi.com
The COVID-19 pandemic prompted rapid research on SARS-CoV-2 pathogenicity.
Consequently, new data can be used to advance the molecular understanding of SARS …
Consequently, new data can be used to advance the molecular understanding of SARS …
GEMIN5 的功能和功能障碍: 了解一种新型神经发育障碍
CH Nelson, UB Pandey - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
The recent identification of a neurodevelopmental disorder with cerebellar atrophy and
motor dysfunction (NEDCAM) has resulted in an increased interest in GEMIN5, a …
motor dysfunction (NEDCAM) has resulted in an increased interest in GEMIN5, a …