The Japanese Society of Hypertension (JSH) revised the Guidelines for the Management of
Hypertension 2014 (JSH 2014), and published the JSH 2019. In the development of the JSH …

Background and Purpose—Numerous imaging techniques have been developed and
applied to evaluate brain hemodynamics. Among these are positron emission tomography …

Normal brain function depends critically on moment-to-moment regulation of oxygen supply
by the bloodstream to meet changing metabolic needs. Neurovascular coupling, a range of …

Background and Purpose—In carotid disease, infarcts can occur in the cortical as well as
internal watershed (WS), or both. Better understanding the pathophysiology of WS infarcts …

Border zone or watershed infarcts are ischemic lesions that occur in characteristic locations
at the junction between two main arterial territories. These lesions constitute approximately …

Since Ogawa et al.(Proc Natl Acad Sci USA 1990; 87: 9868–9872) made the fundamental
discovery of blood oxygenation leveldependent (BOLD) contrast in MRI, most efforts have …

Modern MRI image processing methods have yielded quantitative, morphometric, functional,
and structural assessments of the human brain. These analyses typically exploit carefully …

Cerebral blood flow pressure-passivity results when pressure autoregulation is impaired, or
overwhelmed, and is thought to underlie cerebrovascular injury in the premature infant …

Heart failure (HF) is one of the major causes of death worldwide. Despite the high incidence
of stroke in patients with HF, there has been a controversy as to whether HF itself is a risk …

Heart failure (HF) is a systemic illness with grave implications for bodily functions. The brain,
among other vital organs, often suffers insults as a result of HF, and both anatomic and …