Cryptosporidium is a protozoan parasite of medical and veterinary importance that causes
gastroenteritis in a variety of vertebrate hosts. Several studies have reported different …

Many fungal pathogens undergo morphological transformations during host invasion.
However, the significance of this for fungal pathogenesis is not clear. Both yeast and hyphal …

Candida albicans is the most common human fungal pathogen and causes significant
morbidity and mortality worldwide. Nevertheless, the basic principles of C. albicans …

Virulence is one of a number of possible outcomes of host‐microbe interaction. As such,
microbial virulence is dependent on host factors, as exemplified by the pathogenicity of …

Candida albicans is a dimorphic human pathogen in which the yeast to hyphal switch may
be an important factor in virulence in mammals. This pathogen has recently been shown to …

Candida species, in particular C. albicans, represent a major threat to immunocompromised
patients. Able to exist as a commensal on mucosal surfaces of healthy individuals, these …

Candida albicans is a polymorphic fungus that has the ability to rapidly switch between
yeast and filamentous forms. The morphological transition appears to be a critical virulence …

A half century ago, Max Perutz and John Kendrew determined the crystal structure of two
heme-containing proteins: hemoglobin and myoglobin, respectively. 1, 2 These landmark …

Candida species other than Candida albicans now account for up to 50% of deep
candidiasis cases, yet little attention has been paid to the virulence attributes of these fungi …

Uridine auxotrophy, based on disruption of both URA3 alleles in diploid Candida albicans
strain SC5314, has been widely used to select gene deletion mutants created in this fungus …