Clinical trials of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors or
statin therapy have demonstrated that baseline or treated low-density lipoprotein (LDL) …

Obese patients are at risk for the development of cardiovascular diseases, which can in part
be explained by disturbances in the haemostatic and fibrinolytic systems. Indeed, obese …

Since the first Joint European Societies (European Society of Cardiology, European
Atherosclerosis Society and European Society of Hypertension) Task Force …

Background—Gelatinase B, a matrix metalloproteinase that has proteolytic activity against
connective tissue proteins, has been suggested to be important in the connective tissue …

Background: The prevalence of duodenal carcinoma is much higher in familial
adenomatous polyposis (FAP) than in the background population, and duodenal …

The development of thrombotic disorders in humans is one of the most common causes of
morbidity and mortality in the Western world. Thrombotic disease can be classified in broad …

The products of tobacco combustion are absorbed into the systemic circulation. Absorbed
nicotine stimulates the release of catecholamines, whilst other products (perhaps including …

Plasma fibrinogen is a major determinant of platelet aggregation and blood viscosity. The
decrease in plasma fibrinogen by bezafibrate is associated with a decrease in the risk of …

Fibrinogen is an abundant plasma protein that, when converted to fibrin by thrombin,
provides the main building blocks for the clot. Dys‐, a‐, and hypo‐fibrinogenemias have …

Background In the context of a comprehensive population strategy to reduce tobacco use,
encourage healthy food choices, and increase physical activity for the whole population, the …