Oxygen in the atmosphere is a crucial component for life-sustaining aerobic respiration in
humans. Approximately 95% of oxygen is consumed as energy and ultimately becomes …

The anatomy and physiology of the microcirculation in human skin are complex. Normal
cutaneous microcirculation is organized in two parallel plexuses with capillary loops …

Endogenously produced nitric oxide (NO) has a remarkably diverse range of biological
functions, including a role in neurotransmission, smooth muscle relaxation, and the …

Nitric oxide (NO), a signaling molecule, regulates biological functions in multiple
organs/tissues, including the epidermis, where it impacts permeability barrier homeostasis …

Psoriasis is a chronic immune-mediated hyperproliferative inflammatory skin disease in
which a cytokine network concept is well established. Skin is a major target of oxidative …

Psoriasis is a chronic inflammatory, proliferative skin disease characterized by pathological
skin lesions due to various exogenous and endogenous factors. It is associated with a …

Nitric oxide drives skin repair: Novel functions of an established mediator. Wound healing of
the skin represents a highly ordered process of important tissue movements that aims for a …

Recently, we demonstrated a large induction of inducible nitric oxide synthase (iNOS) during
cutaneous wound repair. In this study, we investigated the role of nitric oxide (NO) for the …

The gaseous free radical nitric oxide is an important biologic mediator with physiologic and
pathophysiologic roles in nearly every organ system. Because of its unique biologic activity …

Nitric oxide (NO) is a free radical which has complex roles in both health and disease. It is
now recognized that NO is essential for a vast spectrum of intracellular and extracellular …