Ovarian cancer prevention and screening

U Menon, C Karpinskyj… - Obstetrics & …, 2018 - journals.lww.com
Financial Disclosure Prof. Menon has stock ownership and has received research funding
from Abcodia Ltd, a UCL spinout company with an interest in biomarkers and commercial …

Current and emerging methods for ovarian cancer screening and diagnostics: a comprehensive review

JM Liberto, SY Chen, IM Shih, TH Wang, TL Wang… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian high-grade serous carcinoma (HGSC) has a 5-year survival rate
of less than 50%, making it one of the most lethal gynecological cancers for women in the …

Ovarian cancer screening: Current status and future directions

Z Nash, U Menon - Best practice & research Clinical obstetrics & …, 2020 - Elsevier
Ovarian cancer is the third most common gynaecological malignancy and the most lethal
worldwide. Most patients are diagnosed with advanced disease which carries significant …

Hereditary ovarian cancer: towards a cost-effective prevention strategy

A Ghose, A Bolina, I Mahajan, SA Raza… - International Journal of …, 2022 - mdpi.com
Ovarian cancer (OC) is the most lethal gynaecological malignancy. The search for a widely
affordable and accessible screening strategy to reduce mortality from OC is still ongoing …

[HTML][HTML] Mortality impact, risks, and benefits of general population screening for ovarian cancer: the UKCTOCS randomised controlled trial.

U Menon, A Gentry-Maharaj, M Burnell… - Health Technology …, 2023 - ncbi.nlm.nih.gov
Mortality impact, risks, and benefits of general population screening for ovarian cancer: the
UKCTOCS randomised controlled trial. - PMC Back to Top Skip to main content NIH NLM Logo …

A review of survival analysis methods used in NICE technology appraisals of cancer treatments: consistency, limitations, and areas for improvement

H Bell Gorrod, B Kearns, J Stevens… - Medical Decision …, 2019 - journals.sagepub.com
Objectives. In June 2011, the National Institute for Health and Care Excellence (NICE)
Decision Support Unit published a Technical Support Document (TSD) providing …

[HTML][HTML] Risk scores to guide referral decisions for people with suspected ovarian cancer in secondary care: a systematic review and cost-effectiveness analysis.

M Westwood, B Ramaekers, S Lang… - Health Technology …, 2018 - europepmc.org
Background Ovarian cancer is the sixth most common cancer in UK women and can be
difficult to diagnose, particularly in the early stages. Risk-scoring can help to guide referral to …

Generalized linear models for flexible parametric modeling of the hazard function

B Kearns, MD Stevenson… - Medical Decision …, 2019 - journals.sagepub.com
Background. Parametric modeling of survival data is important, and reimbursement
decisions may depend on the selected distribution. Accurate predictions require sufficiently …

How uncertain is the survival extrapolation? A study of the impact of different parametric survival models on extrapolated uncertainty about hazard functions, lifetime …

B Kearns, J Stevens, S Ren, A Brennan - Pharmacoeconomics, 2020 - Springer
Abstract Background and Objective The extrapolation of estimated hazard functions can be
an important part of cost-effectiveness analyses. Given limited follow-up time in the sample …

[HTML][HTML] A guide to selecting flexible survival models to inform economic evaluations of cancer immunotherapies

S Palmer, I Borget, T Friede, D Husereau, J Karnon… - Value in Health, 2023 - Elsevier
Objectives Parametric models are routinely used to estimate the benefit of cancer drugs
beyond trial follow-up. The advent of immune checkpoint inhibitors has challenged this …