Glial cells: role of the immune response in ischemic stroke

S Xu, J Lu, A Shao, JH Zhang, J Zhang - Frontiers in immunology, 2020 - frontiersin.org
Ischemic stroke, which accounts for 75–80% of all strokes, is the predominant cause of
morbidity and mortality worldwide. The post-stroke immune response has recently emerged …

Beyond the GFAP-astrocyte protein markers in the brain

AM Jurga, M Paleczna, J Kadluczka, KZ Kuter - Biomolecules, 2021 - mdpi.com
The idea of central nervous system as one-man band favoring neurons is long gone. Now
we all are aware that neurons and neuroglia are team players and constant communication …

Neuroinflammatory astrocyte subtypes in the mouse brain

P Hasel, IVL Rose, JS Sadick, RD Kim… - Nature …, 2021 - nature.com
Astrocytes undergo an inflammatory transition after infections, acute injuries and chronic
neurodegenerative diseases. How this transition is affected by time and sex, its …

[HTML][HTML] Mesenchymal stem cell-derived exosomes as a nanotherapeutic agent for amelioration of inflammation-induced astrocyte alterations in mice

P Xian, Y Hei, R Wang, T Wang, J Yang, J Li, Z Di… - Theranostics, 2019 - ncbi.nlm.nih.gov
Mesenchymal stem cell-derived exosomes (MSC-Exo) have robust anti-inflammatory effects
in the treatment of neurological diseases such as epilepsy, stroke, or traumatic brain injury …

Immune and neuroendocrine mechanisms of stress vulnerability and resilience

C Ménard, ML Pfau, GE Hodes, SJ Russo - Neuropsychopharmacology, 2017 - nature.com
Diagnostic criteria for mood disorders including major depressive disorder (MDD) largely
ignore biological factors in favor of behavioral symptoms. Compounding this paucity of …

[HTML][HTML] Glial cells shape pathology and repair after spinal cord injury

AD Gaudet, LK Fonken - Neurotherapeutics, 2018 - Elsevier
Glial cell types were classified less than 100 years ago by del Rio-Hortega. For instance, he
correctly surmised that microglia in pathologic central nervous system (CNS) were …

Astrocyte activation and reactive gliosis—a new target in stroke?

M Pekny, U Wilhelmsson, T Tatlisumak, M Pekna - Neuroscience letters, 2019 - Elsevier
Stroke is an acute insult to the central nervous system (CNS) that triggers a sequence of
responses in the acute, subacute as well as later stages, with prominent involvement of …

Release of O-GlcNAc transferase inhibitor promotes neuronal differentiation of neural stem cells in 3D bioprinted supramolecular hydrogel scaffold for spinal cord …

X Liu, S Song, Z Chen, C Gao, Y Li, Y Luo, J Huang… - Acta biomaterialia, 2022 - Elsevier
Precise fabrication of biomimetic three-dimensional (3D) structure and effective neuronal
differentiation under the pathological environment are the key to neural stem cell (NSC) …

Enhancing the alignment of the preclinical and clinical stroke recovery research pipeline: Consensus-based core recommendations from the Stroke Recovery and …

D Corbett, ST Carmichael, TH Murphy… - … and neural repair, 2017 - journals.sagepub.com
Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline:
Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation …

Diversity of reactive astrogliosis in CNS pathology: heterogeneity or plasticity?

AJ Moulson, JW Squair, RJM Franklin… - Frontiers in cellular …, 2021 - frontiersin.org
Astrocytes are essential for the development and homeostatic maintenance of the central
nervous system (CNS). They are also critical players in the CNS injury response during …