Orofacial clefts (OFCs) rank as the second most common congenital birth defect in the
United States after Down syndrome and are the most common head and neck congenital …

Orofacial clefts are common birth defects and can occur as isolated, nonsyndromic events or
as part of Mendelian syndromes. There is substantial phenotypic diversity in individuals with …

Orofacial clefts (OFCs) are among the most common birth defects and impart a significant
burden on afflicted individuals and their families. It is increasingly understood that many …

Transcription factors (TFs) participate in a wide range of cellular processes due to their
inherent function as essential regulatory proteins. Their dysfunction has been linked to …

Nonsyndromic cleft lip with or without cleft palate (NSCL±P) is the most common orofacial
birth defect, exhibiting variable prevalence around the world, often attributed to ethnic and …

Nonsyndromic orofacial clefting (nsOFC) is a common, complex congenital disorder. The
most frequent forms are nonsyndromic cleft lip with or without cleft palate (nsCL/P) and …

Orofacial clefts (OFCs) are common (1 in 700 births) congenital malformations that include a
cleft lip (CL) and cleft lip and palate (CLP). These OFC subtypes are also heterogeneous …

Nonsyndromic cleft lip and/or palate (NSCL/P) is a prevalent birth defect of complex etiology.
Previous studies identified mutations in ARHGAP29 associated with an increased risk for …

Three common diseases, isolated cleft lip and cleft palate (CLP), hypothyroidism and thyroid
cancer all map to the FOXE1 locus, but causative variants have yet to be identified. In …

Non‐syndromic cleft lip with or without cleft palate (CL/P) is a common birth defect with a
complex etiology. Numerous genes and environmental factors, and their interactions, are …