Emerging technologies to image tissue metabolism
Due to the implication of altered metabolism in a large spectrum of tissue function and
disease, assessment of metabolic processes becomes essential in managing health. In this …
disease, assessment of metabolic processes becomes essential in managing health. In this …
Magnetic resonance imaging with hyperpolarized agents: methods and applications
In the past decade, hyperpolarized (HP) contrast agents have been under active
development for MRI applications to address the twin challenges of functional and …
development for MRI applications to address the twin challenges of functional and …
Dual‐Echo EPI sequence for integrated distortion correction in 3D time‐resolved hyperpolarized 13C MRI
Purpose To provide built‐in off‐resonance correction in time‐resolved, volumetric
hyperpolarized 13C metabolic imaging by implementing a novel dual‐echo 3D echo‐planar …
hyperpolarized 13C metabolic imaging by implementing a novel dual‐echo 3D echo‐planar …
Acquisition strategies for spatially resolved magnetic resonance detection of hyperpolarized nuclei
GJ Topping, C Hundshammer, L Nagel… - … Resonance Materials in …, 2020 - Springer
Hyperpolarization is an emerging method in magnetic resonance imaging that allows
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …
nuclear spin polarization of gases or liquids to be temporarily enhanced by up to five or six …
Effects of excitation angle strategy on quantitative analysis of hyperpolarized pyruvate
CM Walker, D Fuentes, PEZ Larson… - Magnetic resonance …, 2019 - Wiley Online Library
Purpose Various excitation strategies have been proposed for dynamic imaging of
hyperpolarized agents such as [1‐13C]‐pyruvate, but the impact of these strategies on …
hyperpolarized agents such as [1‐13C]‐pyruvate, but the impact of these strategies on …
Noninvasive interrogation of cancer metabolism with hyperpolarized 13C MRI
This review will highlight recent advances in hyperpolarized 13C MR spectroscopic imaging,
which can be used to noninvasively interrogate tumor metabolism. After providing an …
which can be used to noninvasively interrogate tumor metabolism. After providing an …
Hyperpolarized [1-13C] pyruvate MR spectroscopy detect altered glycolysis in the brain of a cognitively impaired mouse model fed high-fat diet
Higher dietary intakes of saturated fatty acid increase the risk of developing Alzheimer's
disease and dementia, and even in people without diabetes higher glucose levels may be a …
disease and dementia, and even in people without diabetes higher glucose levels may be a …
Hyperpolarised 13C-MRI metabolic and functional imaging: an emerging renal MR diagnostic modality
M Pedersen, S Ursprung, JD Jensen… - … Resonance Materials in …, 2020 - Springer
Magnetic resonance imaging (MRI) is a well-established modality for assessing renal
morphology and function, as well as changes that occur during disease. However, the …
morphology and function, as well as changes that occur during disease. However, the …
Hyperpolarized 13C Magnetic Resonance Spectroscopic Imaging of Pyruvate Metabolism in Murine Breast Cancer Models of Different Metastatic Potential
EB Macdonald, P Begovatz, GP Barton… - Metabolites, 2021 - mdpi.com
This study uses dynamic hyperpolarized [1-13C] pyruvate magnetic resonance
spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between …
spectroscopic imaging (MRSI) to estimate differences in glycolytic metabolism between …
Improved tolerance to off‐resonance in spectral‐spatial EPI of hyperpolarized [1‐13C]pyruvate and metabolites
Purpose For 13C echo‐planar imaging (EPI) with spectral‐spatial excitation, main field
inhomogeneity can result in reduced flip angle and spatial artifacts. A hybrid time‐resolved …
inhomogeneity can result in reduced flip angle and spatial artifacts. A hybrid time‐resolved …