Apoptosis is an intrinsic biochemical, cellular process that regulates cell death and is crucial
for cell survival, cellular homeostasis, and maintaining the optimum functional status …

Polyphenols are an important class of phytochemicals, and several lines of evidence have
demonstrated their beneficial effects in the context of a number of pathologies including …

Amyotrophic lateral sclerosis (ALS) is a rapidly progressing neurodegenerative disease,
characterized by motor neuron (MN) death, for which there are no truly effective treatments …

Background: Exposure to anesthetics during synaptogenesis results in apoptosis and
subsequent cognitive dysfunction in adulthood. Probrain-derived neurotrophic factor …

Extracellular signal regulated kinases 1 and 2 (ERK1/2) regulate cellular responses to a
variety of extracellular stimuli. In the nervous system, ERK1/2 is critical for neuronal …

ERK1/2 MAP kinases are important regulators in cellular signaling, whose activity is
normally reversibly regulated by threonine-tyrosine phosphorylation. In contrast, we have …

Ca2+ influx through NMDA receptors can initiate molecular changes in neurones which may
underlie synaptic plasticity, neuronal development, survival and excitotoxicity. Signalling …

Brain development is influenced by various prenatal, intrapartum, and postnatal events
which may interact with genotype to affect the neural and psychophysiological systems …

Chlorpyrifos, an acetylcholinesterase (AChE) inhibitor, is a widely used organophosphate
pesticide. Recent concern has focused on its neurotoxicity that is not attributable to AChE …

Glycogen synthase kinase (GSK)-3β is a constitutively active, proline-directed
serine/threonine kinase that controls growth modulation and tumorigenesis through multiple …