Cryptogenic stroke: research and practice

S Yaghi, RA Bernstein, R Passman, PM Okin… - Circulation …, 2017 - Am Heart Assoc
Background: Cryptogenic stroke accounts for 30% to 40% of ischemic stroke. It is essential
to determine the possible culprit because this will improve secondary stroke prevention …

Paediatric stroke: pressing issues and promising directions

A Kirton, G deVeber - The Lancet Neurology, 2015 - thelancet.com
Stroke occurs across the lifespan with unique issues in the fetus, neonate, and child. The
past decade has seen substantial advances in paediatric stroke research and clinical care …

Embolic strokes of undetermined source: the case for a new clinical construct

RG Hart, HC Diener, SB Coutts, JD Easton… - The Lancet …, 2014 - thelancet.com
Cryptogenic (of unknown cause) ischaemic strokes are now thought to comprise about 25%
of all ischaemic strokes. Advances in imaging techniques and improved understanding of …

Antithrombotic and thrombolytic therapy for ischemic stroke: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians Evidence …

MG Lansberg, MJ O'Donnell, P Khatri, ES Lang… - Chest, 2012 - Elsevier
Objectives This article provides recommendations on the use of antithrombotic therapy in
patients with stroke or transient ischemic attack (TIA). Methods We generated treatment …

Design of Randomized, double-blind, Evaluation in secondary Stroke Prevention comparing the EfficaCy and safety of the oral Thrombin inhibitor dabigatran etexilate …

HC Diener, JD Easton, CB Granger… - … journal of stroke, 2015 - journals.sagepub.com
Rationale Cryptogenic ischemic strokes constitute 20–30% of ischemic strokes, the majority
of which are embolic strokes of undetermined source. The standard preventive treatment in …

Comparative sensitivity of computed tomography vs. magnetic resonance imaging for detecting acute posterior fossa infarct

DY Hwang, GS Silva, KL Furie, DM Greer - The Journal of emergency …, 2012 - Elsevier
BACKGROUND: Posterior fossa strokes, particularly those related to basilar occlusion, pose
a high risk for progression and poor neurological outcomes. The clinical history and …

Variability in language recovery after first-time stroke

RM Lazar, AE Speizer, JR Festa… - Journal of Neurology …, 2008 - jnnp.bmj.com
Background: Predicting aphasia recovery after stroke has been difficult due to substantial
variability in outcomes. Few studies have characterised the nature and extent of recovery …

Antithrombotic treatments, outcomes, and prognostic factors in acute childhood-onset arterial ischaemic stroke: a multicentre, observational, cohort study

NA Goldenberg, TJ Bernard, HJ Fullerton… - The Lancet …, 2009 - thelancet.com
Background For childhood-onset arterial ischaemic stroke (AIS), treatment trials are lacking
and practices vary from country to country and centre to centre. We aimed to describe …

Rivaroxaban for secondary stroke prevention in patients with embolic strokes of undetermined source: design of the NAVIGATE ESUS randomized trial

RG Hart, M Sharma, H Mundl… - European stroke …, 2016 - journals.sagepub.com
Background Embolic strokes of undetermined source comprise up to 20% of ischemic
strokes. The stroke recurrence rate is substantial with aspirin, widely used for secondary …

Signatures of cardioembolic and large‐vessel ischemic stroke

GC Jickling, H Xu, B Stamova, BP Ander… - Annals of …, 2010 - Wiley Online Library
Objective: The cause of stroke remains unknown or cryptogenic in many patients. We sought
to determine whether gene expression signatures in blood can distinguish between …