Oleanolic acid and its derivatives: biological activities and therapeutic potential in chronic diseases
TB Ayeleso, MG Matumba, E Mukwevho - Molecules, 2017 - mdpi.com
The increasing demand for natural products as an alternative therapy for chronic diseases
has encouraged research into the pharmacological importance of bioactive compounds from …
has encouraged research into the pharmacological importance of bioactive compounds from …
Oleanane-, ursane-, and quinone methide friedelane-type triterpenoid derivatives: Recent advances in cancer treatment
JAR Salvador, AS Leal, AS Valdeira… - European Journal of …, 2017 - Elsevier
Natural pentacyclic triterpenoids (PTs) have been often reported to exhibit a wide range of
biological activities. Among them, the anticancer and anti-inflammatory activities are the …
biological activities. Among them, the anticancer and anti-inflammatory activities are the …
Design and synthesis of pentacyclic triterpene conjugates and their use in medicinal research
J Hodon, L Borkova, J Pokorny, A Kazakova… - European journal of …, 2019 - Elsevier
Triterpenoids are natural products from plants and many other organisms that have various
biological activities, such as antitumor, antiviral, antimicrobial, and protective activities. This …
biological activities, such as antitumor, antiviral, antimicrobial, and protective activities. This …
Gypsogenin Battling for a Front Position in the Pentacyclic Triterpenes Game of Thrones on Anti-Cancer Therapy: A Critical Review—Dedicated to the Memory of …
MO Radwan, HI Abd-Alla, AT Alsaggaf, H El-Mezayen… - Molecules, 2023 - mdpi.com
In the last decade, gypsogenin has attracted widespread attention from medicinal chemists
by virtue of its prominent anti-cancer potential. Despite its late identification, gypsogenin has …
by virtue of its prominent anti-cancer potential. Despite its late identification, gypsogenin has …
Selected plant triterpenoids and their amide derivatives in cancer treatment: A review
Z Özdemir, Z Wimmer - Phytochemistry, 2022 - Elsevier
Medicinal plants have been used to treat different diseases throughout the human history
namely in traditional medicine. Most of the plants mentioned in this review article belong …
namely in traditional medicine. Most of the plants mentioned in this review article belong …
Recent advances in medicinal chemistry of oleanolic acid derivatives
YH Yang, SY Dai, FH Deng, LH Peng, C Li, YH Pei - Phytochemistry, 2022 - Elsevier
Oleanolic acid (OA), a ubiquitous pentacyclic oleanane-type triterpene isolated from edible
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …
and medicinal plants, exhibits a wide spectrum of pharmacological activities and …
[HTML][HTML] Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases
A Sen - World Journal of Clinical Cases, 2020 - ncbi.nlm.nih.gov
Oleanolic acid (OA) and its derivatives are widely found in diverse plants and are naturally
effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles …
effective pentacyclic triterpenoid compounds with broad prophylactic and therapeutic roles …
Harnessing oleanolic acid and its derivatives as modulators of metabolic nuclear receptors
Nuclear receptors (NRs) constitute a superfamily of ligand-activated transcription factors with
a paramount role in ubiquitous physiological functions such as metabolism, growth, and …
a paramount role in ubiquitous physiological functions such as metabolism, growth, and …
Oleanolic acid reprograms the liver to protect against hepatotoxicants, but is hepatotoxic at high doses
J Liu, YF Lu, Q Wu, SF Xu, FG Shi… - Liver …, 2019 - Wiley Online Library
Oleanolic acid (OA) is a triterpenoid that exists widely in fruits, vegetables and medicinal
herbs. OA is included in some dietary supplements and is used as a complementary and …
herbs. OA is included in some dietary supplements and is used as a complementary and …
Hepatoprotective and Antioxidant Capacity of Mallotus repandus Ethyl Acetate Stem Extract against d-Galactosamine-Induced Hepatotoxicity in Rats
Mallotus repandus (M. repandus) is traditionally used to treat muscle pain, itching, fever,
rheumatic arthritis, and a variety of liver disorders. The aim of the present work was to …
rheumatic arthritis, and a variety of liver disorders. The aim of the present work was to …