Bacterial exopolysaccharides: biosynthesis pathways and engineering strategies

J Schmid, V Sieber, B Rehm - Frontiers in microbiology, 2015 - frontiersin.org
Bacteria produce a wide range of exopolysaccharides which are synthesized via different
biosynthesis pathways. The genes responsible for synthesis are often clustered within the …

Biosynthesis of the Pseudomonas aeruginosa Extracellular Polysaccharides, Alginate, Pel, and Psl

MJ Franklin, DE Nivens, JT Weadge… - Frontiers in …, 2011 - frontiersin.org
Pseudomonas aeruginosa thrives in many aqueous environments and is an opportunistic
pathogen that can cause both acute and chronic infections. Environmental conditions and …

Microbial alginate production, modification and its applications

ID Hay, ZU Rehman, MF Moradali… - Microbial …, 2013 - Wiley Online Library
Alginate is an important polysaccharide used widely in the food, textile, printing and
pharmaceutical industries for its viscosifying, and gelling properties. All commercially …

Bacterial exopolysaccharides: Chemical structures, gene clusters and genetic engineering

X Sun, J Zhang - International Journal of Biological Macromolecules, 2021 - Elsevier
In recent decades, the composition, structure, biosynthesis, and function of bacterial
extracellular polysaccharides (EPS) have been extensively studied. EPS are synthesized …

Bacterial biosynthesis of alginates

ID Hay, Z Ur Rehman, A Ghafoor… - Journal of Chemical …, 2010 - Wiley Online Library
Alginates are polysaccharides with many industrial and medical uses, from food additives to
encapsulation agents in the emerging transplantation technologies. Alginate is composed of …

Genetics and regulation of bacterial alginate production

ID Hay, Y Wang, MF Moradali… - Environmental …, 2014 - Wiley Online Library
A vast range of extracellular polysaccharides are produced by bacteria in order to adapt to
and thrive in diverse environmental niches. Many of these polymers have attracted great …

[HTML][HTML] Efflux pumps and microbial biofilm formation

MN Hajiagha, HS Kafil - Infection, Genetics and Evolution, 2023 - Elsevier
Biofilm-related infections are resistant forms of pathogens that are regarded as a medical
problem, particularly due to the spread of multiple drug resistance. One of the factors …

Structural basis for alginate secretion across the bacterial outer membrane

JC Whitney, ID Hay, C Li… - Proceedings of the …, 2011 - National Acad Sciences
Pseudomonas aeruginosa is the predominant pathogen associated with chronic lung
infection among cystic fibrosis patients. During colonization of the lung, P. aeruginosa …

Characterization and mechanical properties investigation of the cellulose/gypsum composite

F Nindiyasari, E Griesshaber… - Journal of …, 2016 - journals.sagepub.com
We synthesized cellulose/gypsum composites in the presence and absence of sodium
alginate and investigated the interaction between the composite components as well as the …

Discovery of novel leptospirosis vaccine candidates using reverse and structural vaccinology

AA Grassmann, FS Kremer, JC Dos Santos… - Frontiers in …, 2017 - frontiersin.org
Leptospira spp. are diderm (two membranes) bacteria that infect mammals causing
leptospirosis, a public health problem with global implications. Thousands of people die …