Artificial intelligence in lung cancer pathology image analysis

S Wang, DM Yang, R Rong, X Zhan, J Fujimoto, H Liu… - Cancers, 2019 - mdpi.com
Objective: Accurate diagnosis and prognosis are essential in lung cancer treatment
selection and planning. With the rapid advance of medical imaging technology, whole slide …

[HTML][HTML] The 2015 World Health Organization classification of lung tumors: impact of genetic, clinical and radiologic advances since the 2004 classification

WD Travis, E Brambilla, AG Nicholson, Y Yatabe… - Journal of thoracic …, 2015 - Elsevier
Abstract The 2015 World Health Organization (WHO) Classification of Tumors of the Lung,
Pleura, Thymus and Heart has just been published with numerous important changes from …

A grading system for invasive pulmonary adenocarcinoma: a proposal from the International Association for the Study of Lung Cancer Pathology Committee

AL Moreira, PSS Ocampo, Y Xia, H Zhong… - Journal of Thoracic …, 2020 - Elsevier
Introduction A grading system for pulmonary adenocarcinoma has not been established.
The International Association for the Study of Lung Cancer pathology panel evaluated a set …

Early and locally advanced non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up

PE Postmus, KM Kerr, M Oudkerk, S Senan… - Annals of …, 2017 - annalsofoncology.org
Lung cancer is the leading cause of cancer mortality worldwide with 1.8 million newly
diagnosed cases, or 13% of all cancers diagnosed, in 2012 [1]. The worldwide numbers are …

Predicting non-small cell lung cancer prognosis by fully automated microscopic pathology image features

KH Yu, C Zhang, GJ Berry, RB Altman, C Ré… - Nature …, 2016 - nature.com
Lung cancer is the most prevalent cancer worldwide, and histopathological assessment is
indispensable for its diagnosis. However, human evaluation of pathology slides cannot …

Pathologist-level classification of histologic patterns on resected lung adenocarcinoma slides with deep neural networks

JW Wei, LJ Tafe, YA Linnik, LJ Vaickus, N Tomita… - Scientific reports, 2019 - nature.com
Classification of histologic patterns in lung adenocarcinoma is critical for determining tumor
grade and treatment for patients. However, this task is often challenging due to the …

Tumor mutation burden as a biomarker in resected non–small-cell lung cancer

S Devarakonda, F Rotolo, MS Tsao, I Lanc… - Journal of Clinical …, 2018 - ascopubs.org
Purpose The survival benefit with adjuvant chemotherapy for patients with resected stage II-
III non–small-cell lung cancer (NSCLC) is modest. Efforts to develop prognostic or predictive …

Adjuvant systemic therapy and adjuvant radiation therapy for stage I to IIIA completely resected non–small-cell lung cancers: American Society of Clinical Oncology …

MG Kris, LE Gaspar, JE Chaft, EB Kennedy… - Journal of Clinical …, 2017 - ascopubs.org
Purpose The panel updated the American Society of Clinical Oncology (ASCO) adjuvant
therapy guideline for resected non–small-cell lung cancers. Methods ASCO convened an …

Automated sample preparation with SP 3 for low‐input clinical proteomics

T Müller, M Kalxdorf, R Longuespée… - Molecular systems …, 2020 - embopress.org
High‐throughput and streamlined workflows are essential in clinical proteomics for
standardized processing of samples from a variety of sources, including fresh‐frozen tissue …

[HTML][HTML] Scientific advances in lung cancer 2015

AS Tsao, GV Scagliotti, PA Bunn Jr, DP Carbone… - Journal of Thoracic …, 2016 - Elsevier
Lung cancer continues to be a major global health problem; the disease is diagnosed in
more than 1.6 million new patients each year. However, significant progress is underway in …