Synthetic 3D extracellular matrices (ECMs) find application in cell studies, regenerative
medicine, and drug discovery. While cells cultured in a monolayer may exhibit unnatural …

Collagens are the most abundant components of the extracellular matrix and many types of
soft tissues. Elastin is another major component of certain soft tissues, such as arterial walls …

Articular cartilage is a load-bearing tissue that lines the surface of bones in diarthrodial
joints. Unfortunately, this avascular tissue has a limited capacity for intrinsic repair …

Neurodegenerative diseases, such as Alzheimer's disease (AD), Parkinson's disease (PD),
Huntington's disease (HD) and amyotrophic lateral sclerosis (ALS), affect millions of people …

Over the past decade, stem cell‐and tumor‐derived organoids are the most promising
models in developmental biology and disease modeling, respectively. The matrix is one of …

Emerging evidence suggests that altered components and posttranslational modifications of
proteins in the extracellular matrix (ECM) may both initiate and drive disease progression …

Unlike adult mammals, adult zebrafish vigorously regenerate lost heart muscle in response
to injury. The epicardium, a mesothelial cell layer enveloping the myocardium, is activated to …

Combining stem cells with biomaterial scaffolds serves as a promising strategy for
engineering tissues for both in vitro and in vivo applications. This updated review details …

Here, it is shown that graphene oxide (GO) can be utilized as both a cell‐adhesion substrate
and a growth factor protein‐delivery carrier for the chondrogenic differentiation of adult stem …

Defining drivers of tumour initiation can provide opportunities to control cancer progression.
Here we report that lysophosphatidic acid receptor 4 (LPAR4) becomes transiently …