Efficiency Enhancement in Peptide Hydrogelators: The Crucial Role of Side Chain Hydrogen Bonding Over Aromatic π–π Interactions

AC Unnikrishnan, BK Das, P Saveri, E Mani… - Langmuir, 2024 - ACS Publications
Short peptide assemblies that form supramolecular hydrogels are stabilized by both
intermolecular noncovalent interactions among amino acid side chains and hydrogen …

Phase separation of multicomponent peptide mixtures into dehydrated clusters with hydrophilic cores

WH Brown, DA Potoyan - Biophysical Journal, 2024 - cell.com
Phase separation of biomolecules underlies the formation and regulation of various
membraneless condensates in cells. How condensates function reliably while surrounded …

Influence of pH on the self-assembly of diphenylalanine peptides: molecular insights from coarse-grained simulations

Y Wang, K Wang, X Zhao, X Xu, T Sun - Soft Matter, 2023 - pubs.rsc.org
Nanostructures fabricated from peptide self-assemblies are attracting increasing attention
owing to their possible applications in biology and nanotechnology. A known example is an …

Tuning the thermostability of GHG gels by salts at different positions on the Hofmeister scale

NS O'Neill, NJ Alvarez, R Schweitzer-Stenner - Scientific reports, 2024 - nature.com
The influence of Hofmeister cations (NH4+, Na+, Mg2+) and anions (H2PO4−, CH3COO−,
Cl−, NO3−) on the thermostability of a GHG hydrogel was investigated. The combined …

Determining the nanostructure and main axis of gly-his-gly fibrils using the amide I'bands in FTIR, VCD, and Raman spectra

N O'Neill, TA Lima, FF Ferreira, NJ Alvarez… - … Acta Part A: Molecular …, 2024 - Elsevier
The zwitterionic tripeptide glycyl-histidine-glycine (GHG) has been shown to self-assemble
into visible crystalline fibrils that form a gel-supporting network with a very high storage …

Impact of glycan nature on structure and viscoelastic properties of glycopeptide hydrogels

J Proksch, MCS Dal Colle, F Heinz… - Journal of Peptide …, 2024 - Wiley Online Library
Mucus is a complex biological hydrogel that acts as a barrier for almost everything entering
or exiting the body. It is therefore of emerging interest for biomedical and pharmaceutical …

The Physics of Protein Structure and Dynamics: When and Why Proteins Fold or Don't Fold

R Schweitzer-Stenner - 2024 - researchdiscovery.drexel.edu
The Physics of Protein Structure and Dynamics looks at various aspects of protein structure
and dynamics from a physico-chemical point of view. It goes into some depth regarding the …

The Self-assembly of Single Amino Acids and Materials Rich in a Particular Amino Acid

A Reji, A Selvaraj, S Jose, DG Nair… - Current Applied …, 2024 - benthamdirect.com
Diseases can result from an excess or deficit of amino acids in the blood. The smallest
biomolecules that can self-assemble are amino acids. Fifteen amino acids, phenylalanine …