This review of the familial tumor syndromes involving the endocrine organs is focused on
discussing the main updates on the upcoming fifth edition of the WHO Classification of …

Parathyroid carcinoma (PC) may occur as part of a complex hereditary syndrome or an
isolated (ie, non‐syndromic) non‐hereditary (ie, sporadic) endocrinopathy. Studies of …

The hyperparathyroidism‐jaw tumor (HPT‐JT) syndrome is an autosomal dominant disorder
characterized by the occurrence of parathyroid tumors in association with ossifying fibromas …

Ossifying fibroma and fibrous dysplasia of the jaw are maxillofacial fibro-osseous lesions
that should be distinguished each other by a pathologist because they show distinct patterns …

Benign fibro-osseous lesions of the craniofacial skeleton (BFOL) are a variant group of
intraosseous disease processes that share similar microscopic features characterized by …

Recent data suggest an increase in the overall incidence of parathyroid disorders, with
primary hyperparathyroidism (PHPT) being the most prevalent parathyroid disorder. PHPT is …

Parathyroid cancer is one of the rarest causes of primary hyperparathyroidism and tends to
present with more severe symptoms than its more benign counterparts. This article details …

The CDC73 gene is mutationally inactivated in hereditary and sporadic parathyroid tumors.
It negatively regulates β-catenin, cyclin D1, and c-MYC. Down-regulation of CDC73 has …

In WHO classification of odontogenic tumors (2005), juvenile ossifying fibroma (JOF) is
divided into juvenile psammomatoid ossifying fibroma (JPOF) and juvenile trabecular …

Context Hyperparathyroidism-jaw tumor (HPT-JT) syndrome is a heritable form of primary
hyperparathyroidism caused by germline inactivating mutations in CDC73 encoding …