Major depressive disorder (MDD) was previously hypothesized to be a disease of
monoamine deficiency in which low levels of monoamines in the synaptic cleft were …

Since the Coronavirus disease 2019 (COVID-19) pandemic, caused by Severe Acute
Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was announced, we had an …

An extensive literature on childhood adversity and neurodevelopment has emerged over the
past decade. We evaluate two conceptual models of adversity and neurodevelopment—the …

The new coronavirus has been present for two years and has had a widespread and
sustained impact worldwide. There is growing evidence in the literature that COVID-19 may …

Exposure to early life adversity is associated with chronic stress and a range of stress-
related health problems in adulthood. Since chronic stress debilitates activity in the …

Background Childhood maltreatment has been associated with significant impairment in
social, emotional and behavioural functioning later in life. Nevertheless, some individuals …

Background: This systematic review aimed to summarize evidence reporting epigenetic
and/or neuro-immuno-endocrine embedding of adverse childhood events (ACEs) in …

Background Childhood maltreatment is one of the most important preventable risk factors for
a wide variety of psychiatric disorders. Further, when psychiatric disorders emerge in …

Since the brain was found to be somehow flexible, plastic, researchers worldwide have
been trying to comprehend its fundamentals to better understand the brain itself, make …

Recent focus on the consequences of early life adversity (ELA) in neurobiological research
led to a variety of findings suggesting alterations in several physiological systems, such as …