The role of osteoblasts in energy homeostasis
N Dirckx, MC Moorer, TL Clemens… - Nature Reviews …, 2019 - nature.com
Osteoblasts are specialized mesenchymal cells that synthesize bone matrix and coordinate
the mineralization of the skeleton. These cells work in harmony with osteoclasts, which …
the mineralization of the skeleton. These cells work in harmony with osteoclasts, which …
Lipocalin-2: a master mediator of intestinal and metabolic inflammation
AR Moschen, TE Adolph, RR Gerner, V Wieser… - Trends in Endocrinology …, 2017 - cell.com
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is
released by various cell types and is an attractive biomarker of inflammation, ischemia …
released by various cell types and is an attractive biomarker of inflammation, ischemia …
[HTML][HTML] Obesity drives STAT-1-dependent NASH and STAT-3-dependent HCC
Obesity is a major driver of cancer, especially hepatocellular carcinoma (HCC). The
prevailing view is that non-alcoholic steatohepatitis (NASH) and fibrosis or cirrhosis are …
prevailing view is that non-alcoholic steatohepatitis (NASH) and fibrosis or cirrhosis are …
[HTML][HTML] The role of innate immune cells in nonalcoholic fatty liver disease
M Nati, KJ Chung, T Chavakis - Journal of Innate Immunity, 2022 - karger.com
Nonalcoholic fatty liver disease (NAFLD) is a very common hepatic pathology featuring
steatosis and is linked to obesity and related conditions, such as the metabolic syndrome …
steatosis and is linked to obesity and related conditions, such as the metabolic syndrome …
Role of neutrophils in the pathogenesis of nonalcoholic steatohepatitis
Nonalcoholic fatty liver disease (NAFLD) includes a spectrum of liver disorders, from fatty
liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma …
liver to nonalcoholic steatohepatitis (NASH), cirrhosis, and hepatocellular carcinoma …
Neutrophil gelatinase-associated lipocalin is a biomarker of acute-on-chronic liver failure and prognosis in cirrhosis
X Ariza, I Graupera, M Coll, E Solà, R Barreto… - Journal of …, 2016 - Elsevier
Background & Aims Acute-on-chronic liver failure (ACLF) is a syndrome that occurs in
cirrhosis characterized by organ failure (s) and high mortality rate. There are no biomarkers …
cirrhosis characterized by organ failure (s) and high mortality rate. There are no biomarkers …
Diverse functional roles of lipocalin-2 in the central nervous system
Abstract Lipocalin-2 (LCN2) is an acute phase protein with multiple functions that has
garnered a great deal of interest over the last decade. However, its precise role in the …
garnered a great deal of interest over the last decade. However, its precise role in the …
Lipocalin 2 induces neuroinflammation and blood-brain barrier dysfunction through liver-brain axis in murine model of nonalcoholic steatohepatitis
Background Recent clinical and basic research implicated a strong correlation between
NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and …
NAFLD/NASH phenotypes with ectopic manifestations including neuroinflammation and …
Lipocalin 2 (LCN2) expression in hepatic malfunction and therapy
A Asimakopoulou, S Weiskirchen… - Frontiers in …, 2016 - frontiersin.org
Lipocalin 2 (LCN2) is a secreted protein that belongs to the Lipocalins, a group of
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …
transporters of small lipophilic molecules such as steroids, lipopolysaccharides, iron, and …
The role of neutrophils in innate immunity-driven nonalcoholic steatohepatitis: lessons learned and future promise
L Wu, X Gao, Q Guo, J Li, J Yao, K Yan, Y Xu… - Hepatology …, 2020 - Springer
The enrichment of innate immune cells and the enhanced inflammation represent the
hallmark of non-alcoholic steatohepatitis (NASH), the advanced subtype with a significantly …
hallmark of non-alcoholic steatohepatitis (NASH), the advanced subtype with a significantly …