The multiple roles of life stress in metabolic disorders
The activation of stress-related neuroendocrine systems helps to maintain homeostasis, but
excessive stress can damage body functions. We review current evidence from basic …
excessive stress can damage body functions. We review current evidence from basic …
High cortisol and the risk of dementia and Alzheimer's disease: a review of the literature
Introduction: Cortisol effects on the brain are exerted through two distinct receptors, inducing
complex and even opposite effects on the cerebral structures implicated in the various …
complex and even opposite effects on the cerebral structures implicated in the various …
The neurobiology of stress: Vulnerability, resilience, and major depression
H Akil, EJ Nestler - Proceedings of the National Academy of …, 2023 - National Acad Sciences
Over the past few years, the perceived level of psychological stress has risen dramatically
across the globe due to a combination of events including the long-lasting Covid-19 …
across the globe due to a combination of events including the long-lasting Covid-19 …
Primary aldosteronism—a multidimensional syndrome
Primary aldosteronism is a common cause of hypertension and is a risk factor for
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
cardiovascular and renal morbidity and mortality, via mechanisms mediated by both …
[HTML][HTML] Stress-induced plasticity and functioning of ventral tegmental dopamine neurons
EH Douma, ER de Kloet - Neuroscience & Biobehavioral Reviews, 2020 - Elsevier
The ventral tegmental area dopamine (VTA-DA) mesolimbic circuit processes emotional,
motivational, and social reward associations together with their more demanding cognitive …
motivational, and social reward associations together with their more demanding cognitive …
[HTML][HTML] Coping with the forced swim stressor: Current state-of-the-art
ML Molendijk, ER de Kloet - Behavioural brain research, 2019 - Elsevier
The forced swim test (FST) for rodents does not model despair or helplessness. It also is not
a read-out for depression, anxiety, psychomotor retardation or autism, because these are …
a read-out for depression, anxiety, psychomotor retardation or autism, because these are …
The expanding spectrum of primary aldosteronism: implications for diagnosis, pathogenesis, and treatment
Primary aldosteronism is characterized by aldosterone secretion that is independent of renin
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …
and angiotensin II and sodium status. The deleterious effects of primary aldosteronism are …
Polystyrene nanoplastics disrupt glucose metabolism and cortisol levels with a possible link to behavioural changes in larval zebrafish
NR Brun, P Van Hage, ER Hunting… - Communications …, 2019 - nature.com
Plastic nanoparticles originating from weathering plastic waste are emerging contaminants
in aquatic environments, with unknown modes of action in aquatic organisms. Recent …
in aquatic environments, with unknown modes of action in aquatic organisms. Recent …
Brain mechanisms of HPA axis regulation: neurocircuitry and feedback in context Richard Kvetnansky lecture
Regulation of stress reactivity is a fundamental priority of all organisms. Stress responses
are critical for survival, yet can also cause physical and psychological damage. This review …
are critical for survival, yet can also cause physical and psychological damage. This review …
Intranasal insulin for Alzheimer's disease
M Hallschmid - CNS drugs, 2021 - Springer
Brain insulin signaling contributes to memory function and might be a viable target in the
prevention and treatment of memory impairments including Alzheimer's disease. This short …
prevention and treatment of memory impairments including Alzheimer's disease. This short …