Motivated by the promises of gene therapy, there is great interest in developing non-viral
lipid-based vectors for therapeutic applications due to their low immunogenicity, low toxicity …

The diverse structure and regulated deformation of lipid bilayer membranes are among a
cell's most fascinating features. Artificial membrane-bound vesicles, known as liposomes …

Vesicles are hollow aggregates, composed of bilayers of amphiphilic molecules, dispersed
into and filled with a liquid solvent. These aggregates can be formed either as equilibrium or …

The release of cytochrome c from mitochondria is a key signaling mechanism in apoptosis.
Although extramitochondrial proteins are thought to initiate this release, the exact …

Poly (ethylene glycol)(PEG) is a polymer used widely in drug delivery to create “stealth”
nanoparticles (NPs); PEG coatings suppress NP detection and clearance by the immune …

Lipopolysaccharide (LPS) is a unique lipoglycan, with two major physiological roles: 1), as a
major structural component of the outer membrane of Gram-negative bacteria and 2), as a …

We present a novel platform for investigating the composition-specific interactions of
proteins (or other biologically relevant molecules) with model membranes composed of …

Bundles of taxol-stabilized microtubules (MTs)—hollow tubules comprised of assembled αβ-
tubulin heterodimers—spontaneously assemble above a critical concentration of tetravalent …

The prospects of gene therapy have generated unprecedented interest in the properties and
structures of complexes of nucleic acids (NAs) with cationic liposomes (CLs), which are used …

Context: This study presents novel nanostructured oil-in-water (o/w) mists based on self-
nanoemulsifying (SNE) mixtures capable of delivering poorly water-soluble drugs into the …