Renal cell carcinoma as a metabolic disease: an update on main pathways, potential biomarkers, and therapeutic targets
NA di Meo, F Lasorsa, M Rutigliano, D Loizzo… - International Journal of …, 2022 - mdpi.com
Clear cell renal cell carcinoma (ccRCC) is the most frequent histological kidney cancer
subtype. Over the last decade, significant progress has been made in identifying the genetic …
subtype. Over the last decade, significant progress has been made in identifying the genetic …
Immune checkpoint inhibitors in renal cell carcinoma: molecular basis and rationale for their use in clinical practice
F Lasorsa, NA di Meo, M Rutigliano, M Milella, M Ferro… - Biomedicines, 2023 - mdpi.com
Renal cell carcinoma (RCC) is the seventh most common cancer in men and the ninth most
common cancer in women worldwide. There is plenty of evidence about the role of the …
common cancer in women worldwide. There is plenty of evidence about the role of the …
The dark side of lipid metabolism in prostate and renal carcinoma: novel insights into molecular diagnostic and biomarker discovery
NA di Meo, F Lasorsa, M Rutigliano… - Expert Review of …, 2023 - Taylor & Francis
Introduction Lipidomics focuses on the in-depth analysis of lipids, which are crucial
macromolecules involved in a wide range of metabolic pathways. The increased …
macromolecules involved in a wide range of metabolic pathways. The increased …
Cellular and molecular players in the tumor microenvironment of renal cell carcinoma
F Lasorsa, M Rutigliano, M Milella, M Ferro… - Journal of Clinical …, 2023 - mdpi.com
Globally, clear-cell renal cell carcinoma (ccRCC) represents the most prevalent type of
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …
kidney cancer. Surgery plays a key role in the treatment of this cancer, although one third of …
MUC1 expression affects the immunoflogosis in renal cell carcinoma microenvironment through complement system activation and immune infiltrate modulation
G Lucarelli, GS Netti, M Rutigliano, F Lasorsa… - International Journal of …, 2023 - mdpi.com
Mucin1 (MUC1), a glycoprotein associated with an aggressive cancer phenotype and
chemoresistance, is aberrantly overexpressed in a subset of clear cell renal cell carcinoma …
chemoresistance, is aberrantly overexpressed in a subset of clear cell renal cell carcinoma …
The role of MUC1 in renal cell carcinoma
M Milella, M Rutigliano, F Lasorsa, M Ferro, R Bianchi… - Biomolecules, 2024 - mdpi.com
Mucins are a family of high-molecular-weight glycoproteins. MUC1 is widely studied for its
role in distinct types of cancers. In many human epithelial malignancies, MUC1 is frequently …
role in distinct types of cancers. In many human epithelial malignancies, MUC1 is frequently …
Activation of the kynurenine pathway predicts poor outcome in patients with clear cell renal cell carcinoma
G Lucarelli, M Rutigliano, M Ferro, A Giglio… - … Oncology: Seminars and …, 2017 - Elsevier
Objective To investigate the expression of the kynurenine (KYN) pathway components and
the prognostic role of the KYN-to-tryptophan ratio (KTR) in a cohort of patients with clear cell …
the prognostic role of the KYN-to-tryptophan ratio (KTR) in a cohort of patients with clear cell …
The functions of long non-coding RNA (lncRNA)-MALAT-1 in the pathogenesis of renal cell carcinoma
O Anbiyaee, A Moalemnia, F Ghaedrahmati… - BMC nephrology, 2023 - Springer
Renal cell carcinoma (RCC), a prevalent form of renal malignancy, is distinguished by its
proclivity for robust tumor proliferation and metastatic dissemination. Long non-coding RNAs …
proclivity for robust tumor proliferation and metastatic dissemination. Long non-coding RNAs …
Integrating tumor and healthy epithelium in a micro-physiology multi-compartment approach to study renal cell carcinoma pathophysiology
M Somova, S Simm, A Padmyastuti, J Ehrhardt… - Scientific Reports, 2024 - nature.com
The advent of micro-physiological systems (MPS) in biomedical research has enabled the
introduction of more complex and relevant physiological into in vitro models. The recreation …
introduction of more complex and relevant physiological into in vitro models. The recreation …
[HTML][HTML] Identification of an immune-related risk signature for predicting prognosis in clear cell renal cell carcinoma
X Hua, J Chen, Y Su, C Liang - Aging (Albany NY), 2020 - ncbi.nlm.nih.gov
Immune status affects the initiation and progression of clear cell renal cell carcinoma
(ccRCC), the most common subtype of renal cell carcinoma. In this study, we identified an …
(ccRCC), the most common subtype of renal cell carcinoma. In this study, we identified an …