Babesiosis as a potential threat for bovine production in China

L He, RG Bastos, Y Sun, G Hua, G Guan, J Zhao… - Parasites & vectors, 2021 - Springer
Babesiosis is a tick-borne disease with global impact caused by parasites of the phylum
Apicomplexa, genus Babesia. Typically, acute bovine babesiosis (BB) is characterized by …

Exploring the landscape of Babesia bovis vaccines: progress, challenges, and opportunities

JHM Santos, HV Siddle, A Raza, DI Stanisic… - Parasites & …, 2023 - Springer
Bovine babesiosis, caused by different Babesia spp. such as B. bovis, B. bigemina, B.
divergens, and B. major, is a global disease that poses a serious threat to livestock …

Comparative genomic analysis of Babesia duncani responsible for human babesiosis

J Wang, K Chen, J Yang, S Zhang, Y Li, G Liu, J Luo… - BMC biology, 2022 - Springer
Background Human babesiosis, caused by parasites of the genus Babesia, is an emerging
and re-emerging tick-borne disease that is mainly transmitted by tick bites and infected …

Identification of novel immune correlates of protection against acute bovine babesiosis by superinfecting cattle with in vitro culture attenuated and virulent Babesia …

RG Bastos, JM Laughery, S Ozubek, HF Alzan… - Frontiers in …, 2022 - frontiersin.org
The apicomplexan tickborne parasites Babesia bovis and B. bigemina are the major
causative agents of bovine babesiosis, a disease that negatively affects the cattle industry …

Vaccination with an in vitro culture attenuated Babesia bovis strain safely protects highly susceptible adult cattle against acute bovine babesiosis

RG Bastos, J Capelli-Peixoto, JM Laughery… - Frontiers in …, 2023 - frontiersin.org
Introduction Live in vivo attenuated Babesia bovis vaccines produced by sequential
passages in splenectomized calves have historically been used to control acute bovine …

A Culture-Adapted Strain of Babesia bovis Has Reduced Subpopulation Complexity and Is Unable to Complete Its Natural Life Cycle in Ticks

HF Alzan, RG Bastos, JM Laughery… - Frontiers in Cellular …, 2022 - frontiersin.org
Babesia bovis natural field strains are composed of several geno-phenotypically distinct
subpopulations. This feature, together with possible epigenetic modifications, may facilitate …

Vaccination of cattle with the Babesia bovis sexual-stage protein HAP2 abrogates parasite transmission by Rhipicephalus microplus ticks

MG Silva, RG Bastos, JM Laughery, HF Alzan… - npj Vaccines, 2023 - nature.com
The apicomplexan parasite Babesia bovis is responsible for bovine babesiosis, a poorly
controlled tick-borne disease of global impact. The widely conserved gametocyte protein …

Current vaccines, experimental immunization trials, and new perspectives to control selected vector borne blood parasites of veterinary importance

HF Alzan, MS Mahmoud, CE Suarez - Frontiers in Veterinary Science, 2024 - frontiersin.org
Parasite infections transmitted by vectors such as ticks and blood-sucking arthropods pose a
significant threat to both human and animal health worldwide and have a substantial …

Identification of CCp5 and FNPA as Novel Non-canonical Members of the CCp Protein Family in Babesia bovis

S Ozubek, HF Alzan, RG Bastos… - Frontiers in Veterinary …, 2022 - frontiersin.org
Bovine babesiosis, caused by Babesia bovis, is an economically significant tick-borne
disease that imposes restrictions to livestock production worldwide. Current methods to …

Unraveling the Complexity of the Rhomboid Serine Protease 4 Family of Babesia bovis Using Bioinformatics and Experimental Studies

R Gallenti, HE Hussein, HF Alzan, CE Suarez, M Ueti… - Pathogens, 2022 - mdpi.com
Babesia bovis, a tick-transmitted apicomplexan protozoon, infects cattle in tropical and
subtropical regions around the world. In the apicomplexans Toxoplasma gondii and …