Post-stroke depression: mechanisms and pharmacological treatment
Depression, the most frequent psychiatric disorder following ischaemic stroke, negatively
affects survivals' functional outcome, response to rehabilitation and quality of life …
affects survivals' functional outcome, response to rehabilitation and quality of life …
Safety and Efficacy of SSRIs in Improving Poststroke Recovery: A Systematic Review and Meta‐Analysis
HM Kalbouneh, AA Toubasi, FH Albustanji… - Journal of the …, 2022 - Am Heart Assoc
Background Several studies investigated the role of selective serotonin reuptake inhibitors
(SSRIs) in improving poststroke recovery; thus, we have decided to conduct this systematic …
(SSRIs) in improving poststroke recovery; thus, we have decided to conduct this systematic …
Safety and efficacy of fluoxetine on functional recovery after acute stroke (EFFECTS): a randomised, double-blind, placebo-controlled trial
E Lundström, E Isaksson, P Näsman, P Wester… - The Lancet …, 2020 - thelancet.com
Background Studies have suggested that fluoxetine could improve neurological recovery
after stroke. The Efficacy oF Fluoxetine—a randomisEd Controlled Trial in Stroke (EFFECTS) …
after stroke. The Efficacy oF Fluoxetine—a randomisEd Controlled Trial in Stroke (EFFECTS) …
Safety and efficacy of fluoxetine on functional outcome after acute stroke (AFFINITY): a randomised, double-blind, placebo-controlled trial
Background Trials of fluoxetine for recovery after stroke report conflicting results. The
Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral …
Assessment oF FluoxetINe In sTroke recoverY (AFFINITY) trial aimed to show if daily oral …
European Academy of Neurology and European Federation of Neurorehabilitation Societies guideline on pharmacological support in early motor rehabilitation after …
E Beghi, H Binder, C Birle, N Bornstein… - European Journal of …, 2021 - Wiley Online Library
Background and purpose Early pharmacological support for post‐stroke neurorehabilitation
has seen an abundance of mixed results from clinical trials, leaving practitioners at a loss …
has seen an abundance of mixed results from clinical trials, leaving practitioners at a loss …
Persistent post-stroke depression in mice following unilateral medial prefrontal cortical stroke
F Vahid-Ansari, DC Lagace, PR Albert - Translational psychiatry, 2016 - nature.com
Post-stroke depression (PSD) is a common outcome following stroke that is associated with
poor recovery. To develop a preclinical model of PSD, we targeted a key node of the …
poor recovery. To develop a preclinical model of PSD, we targeted a key node of the …
Poststroke depression: an update
RG Robinson, RE Jorge… - The Journal of …, 2024 - Am Neuropsych Assoc
The presence of neuropsychiatric disorders after stroke has been recognized for more than
100 years, but controlled systematic studies did not begin until the 1970s. The most clinically …
100 years, but controlled systematic studies did not begin until the 1970s. The most clinically …
Evaluating mesenchymal stem cell therapy for sepsis with preclinical meta-analyses prior to initiating a first-in-human trial
Evaluation of preclinical evidence prior to initiating early-phase clinical studies has typically
been performed by selecting individual studies in a non-systematic process that may …
been performed by selecting individual studies in a non-systematic process that may …
Selective serotonin reuptake inhibitors to improve outcome in acute ischemic stroke: possible mechanisms and clinical evidence
T Siepmann, AI Penzlin, J Kepplinger… - Brain and …, 2015 - Wiley Online Library
Background Several clinical studies have indicated that selective serotonin reuptake
inhibitors (SSRI s) administered in patients after acute ischemic stroke can improve clinical …
inhibitors (SSRI s) administered in patients after acute ischemic stroke can improve clinical …
Systematic review and meta-analysis of the efficacy of interleukin-1 receptor antagonist in animal models of stroke: an update
SK McCann, F Cramond, MR Macleod… - Translational stroke …, 2016 - Springer
Summary/Abstract Interleukin-1 receptor antagonist (IL-1 RA) is an anti-inflammatory protein
used clinically to treat rheumatoid arthritis and is considered a promising candidate therapy …
used clinically to treat rheumatoid arthritis and is considered a promising candidate therapy …