Etiology and risk factors for rheumatoid arthritis: a state-of-the-art review
VC Romão, JE Fonseca - Frontiers in medicine, 2021 - frontiersin.org
Rheumatoid arthritis (RA) is the most common systemic inflammatory rheumatic disease. It is
associated with significant burden at the patient and societal level. Extensive efforts have …
associated with significant burden at the patient and societal level. Extensive efforts have …
Smoking and rheumatoid arthritis
K Chang, SM Yang, SH Kim, KH Han, SJ Park… - International journal of …, 2014 - mdpi.com
Rheumatoid arthritis (RA) is a chronic inflammatory disease caused by both genetic and
environmental factors. Smoking has been implicated as one of the most important extrinsic …
environmental factors. Smoking has been implicated as one of the most important extrinsic …
Autoantibodies and B Cells: The ABC of rheumatoid arthritis pathophysiology
M Volkov, KA van Schie… - Immunological …, 2020 - Wiley Online Library
Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint inflammation. In
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …
the last few decades, new insights into RA‐specific autoantibodies and B cells have greatly …
Emerging roles of SIRT6 in human diseases and its modulators
The biological functions of sirtuin 6 (SIRT6; eg, deacetylation, defatty‐acylation, and mono‐
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
ADP‐ribosylation) play a pivotal role in regulating lifespan and several fundamental …
Epigenetics in rheumatoid arthritis
Epigenetics in rheumatoid arthritis : Current Opinion in Rheumatology Epigenetics in rheumatoid
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
arthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe Get …
Sirtuin family in autoimmune diseases
Z Tao, Z Jin, J Wu, G Cai, X Yu - Frontiers in Immunology, 2023 - frontiersin.org
In recent years, epigenetic modifications have been widely researched. As humans age,
environmental and genetic factors may drive inflammation and immune responses by …
environmental and genetic factors may drive inflammation and immune responses by …
[HTML][HTML] Delivery of long non-coding RNA NEAT1 by peripheral blood monouclear cells-derived exosomes promotes the occurrence of rheumatoid arthritis via the …
Y Rao, Y Fang, W Tan, D Liu, Y Pang, X Wu… - Frontiers in Cell and …, 2020 - frontiersin.org
Emerging evidence has pointed out the importance of long non-coding RNAs (lncRNAs) in
multiple diseases, the knowledge of rheumatoid arthritis (RA)-associated lncRNAs remains …
multiple diseases, the knowledge of rheumatoid arthritis (RA)-associated lncRNAs remains …
Disease mechanisms in preclinical rheumatoid arthritis: A narrative review
VC Romão, JE Fonseca - Frontiers in Medicine, 2022 - frontiersin.org
In the last decades, the concept of preclinical rheumatoid arthritis (RA) has become
established. In fact, the discovery that disease mechanisms start years before the onset of …
established. In fact, the discovery that disease mechanisms start years before the onset of …
Long non-coding RNA PVT1 knockdown suppresses fibroblast-like synoviocyte inflammation and induces apoptosis in rheumatoid arthritis through demethylation of …
CW Zhang, X Wu, D Liu, W Zhou, W Tan… - Journal of biological …, 2019 - Springer
Background As a type of chronic autoimmune joint disease, rheumatoid arthritis (RA) is a
disorder, characterized by a variety of physical symptoms as well as RA fibroblast-like …
disorder, characterized by a variety of physical symptoms as well as RA fibroblast-like …
Myeloid sirtuin 6 deficiency accelerates experimental rheumatoid arthritis by enhancing macrophage activation and infiltration into synovium
SJ Woo, HS Noh, NY Lee, YH Cheon, SM Yi… - …, 2018 - thelancet.com
Background We recently reported that myeloid sirtuin 6 (Sirt6) is a critical determinant of
phenotypic switching and the migratory responses of macrophages. Given the prominent …
phenotypic switching and the migratory responses of macrophages. Given the prominent …