Background The regulatory mechanisms involved in mitochondrial quality control (MQC)
dysfunction during septic cardiomyopathy (SCM) remain incompletely characterized …

Background & Aims Machine perfusion is increasingly being tested in clinical
transplantation. Despite this, the number of large prospective clinical trials remains limited …

Temperature homeostasis is critical for cells to perform their physiological functions. Among
the diverse methods for temperature detection, fluorescent temperature probes stand out as …

Background VA-ECMO can greatly reduce mortality in critically ill patients, and hypothermia
attenuates the deleterious effects of ischemia–reperfusion injury. We aimed to study the …

Rat brain and heart display different endogenous protective responses against hypobaric
hypoxia in an age-dependent way. The aim of the present work was to evaluate the effects of …

Rationale: Mitochondria are key organelles involved in cell survival and death during the
acute phenomena of myocardial ischemia-reperfusion (ie, myocardial infarction). To …

Life is based on a highly specific combination of atoms, metabolism, and genetics which
eventually reflects the chemistry of the Universe which is composed of hydrogen, oxygen …

Disruption of corticospinal tracts (CST) is a leading factor for motor impairments following
intracerebral hemorrhage (ICH) in the striatum. Previous studies have shown that …

Uncertainty exists regarding whether cyclophilin D (CypD), a mitochondrial matrix protein
that plays a key role in ischemia-reperfusion injury, can be a pharmacological target for …