Sepsis remains a significant cause of neonatal mortality and morbidity, especially in low-and
middle-income countries. Neonatal sepsis presents with nonspecific signs and symptoms …

Sepsis is among the most common causes of death in hospitals. It arises from the host
response to infection. Currently, diagnosis relies on nonspecific physiological criteria and …

In January 2015, the Eunice Kennedy Shriver National Institute of Child Health and Human
Development invited an expert panel to a workshop to address numerous knowledge gaps …

Objective The purpose of this study was to compare intraamniotic inflammation vs microbial
invasion of the amniotic cavity (MIAC) as predictors of adverse outcome in preterm labor with …

Why certain viruses cross the physical barrier of the human placenta but others do not is
incompletely understood. Over the past 20 years, we have gained deeper knowledge of …

Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Sepsis or serious infection within the first 4 weeks of life kills more than 1 million newborns
globally every year. 1 The attack rate for neonatal sepsis is variable (from< 1% to> 35% of …

Intra-amniotic infection and inflammation are major causes of preterm birth (PTB). However,
intra-amniotic inflammation is often detected in the absence of infection. This may partly be …

Preterm birth, the leading cause of death in children under 5 years, may be caused by
inflammation triggered by ascending vaginal infection. About 2 million cervical cerclages are …

Chorioamnionitis is a common cause of preterm birth and may cause adverse neonatal
outcomes, including neurodevelopmental sequelae. Chorioamnionitis has been marked to a …