Some of the clinical manifestations of multiple sclerosis, such as memory impairment and
depression, are, at least partly, related to involvement of the hippocampus. Pathological …

The feeding of cuprizone (CPZ) to animals has been extensively used to model the
processes of demyelination and remyelination, with many papers adopting a narrative linked …

Neuroaxonal pathology is a main determinant of disease progression in multiple sclerosis;
however, its underlying pathophysiological mechanisms, including its link to inflammatory …

Objective Intrathecal inflammation, compartmentalized in cerebrospinal fluid (CSF) and in
meningeal infiltrates, has fundamental role in inflammation, demyelination, and neuronal …

Seizure is one of the manifestations of central nervous system inflammatory demyelinating
diseases, which mainly include multiple sclerosis (MS), aquaporin 4 antibody‐positive …

Quantification methods based on the acquisition of diffusion magnetic resonance imaging
(dMRI) with multiple diffusion weightings (eg, multi-shell) are becoming increasingly applied …

Diffusion tensor imaging (DTI) has been established its usefulness in evaluating normal-
appearing white matter (NAWM) and other lesions that are difficult to evaluate with routine …

Multiple sclerosis (MS) patients are three to six times more likely to develop epilepsy
compared to the rest of the population. Seizures are more common in patients with early …

Cognitive impairment is a common and seriously debilitating symptom of various mental and
neurological disorders including autism, attention deficit hyperactivity disorder, multiple …

Background: Epilepsy development during the course of multiple sclerosis (MS) is
considered to be the result of cortical pathology. However, no long-term data exist on …