Bioprospecting of microbial strains for biofuel production: metabolic engineering, applications, and challenges

MF Adegboye, OB Ojuederie, PM Talia… - Biotechnology for …, 2021 - Springer
The issues of global warming, coupled with fossil fuel depletion, have undoubtedly led to
renewed interest in other sources of commercial fuels. The search for renewable fuels has …

Recent advances in systems and synthetic biology approaches for developing novel cell-factories in non-conventional yeasts

P Patra, M Das, P Kundu, A Ghosh - Biotechnology Advances, 2021 - Elsevier
Microbial bioproduction of chemicals, proteins, and primary metabolites from cheap carbon
sources is currently an advancing area in industrial research. The model yeast …

A consensus S. cerevisiae metabolic model Yeast8 and its ecosystem for comprehensively probing cellular metabolism

H Lu, F Li, BJ Sánchez, Z Zhu, G Li, I Domenzain… - Nature …, 2019 - nature.com
Genome-scale metabolic models (GEMs) represent extensive knowledgebases that provide
a platform for model simulations and integrative analysis of omics data. This study …

Transforming yeast peroxisomes into microfactories for the efficient production of high-value isoprenoids

S Dusséaux, WT Wajn, Y Liu, C Ignea… - Proceedings of the …, 2020 - National Acad Sciences
Current approaches for the production of high-value compounds in microorganisms mostly
use the cytosol as a general reaction vessel. However, competing pathways and metabolic …

Recombination machinery engineering facilitates metabolic engineering of the industrial yeast Pichia pastoris

P Cai, X Duan, X Wu, L Gao, M Ye… - Nucleic Acids …, 2021 - academic.oup.com
The industrial yeast Pichia pastoris has been harnessed extensively for production of
proteins, and it is attracting attention as a chassis cell factory for production of chemicals …

Lipid production in Yarrowia lipolytica is maximized by engineering cytosolic redox metabolism

K Qiao, TM Wasylenko, K Zhou, P Xu… - Nature …, 2017 - nature.com
Microbial factories have been engineered to produce lipids from carbohydrate feedstocks for
production of biofuels and oleochemicals. However, even the best yields obtained to date …

Engineering Yarrowia lipolytica as a platform for synthesis of drop-in transportation fuels and oleochemicals

P Xu, K Qiao, WS Ahn… - Proceedings of the …, 2016 - National Acad Sciences
Harnessing lipogenic pathways and rewiring acyl-CoA and acyl-ACP (acyl carrier protein)
metabolism in Yarrowia lipolytica hold great potential for cost-efficient production of diesel …

Biofuels, biodiesel and biohydrogen production using bioprocesses. A review

RK Srivastava, NP Shetti, KR Reddy… - Environmental …, 2020 - Springer
Energy demands, pollution and global warming induced by globalization are rising, thus
calling for alternative sources of energies. In particular, biofuels are increasingly used for …

Recent advances in metabolic engineering of Saccharomyces cerevisiae: new tools and their applications

J Lian, S Mishra, H Zhao - Metabolic engineering, 2018 - Elsevier
Metabolic engineering aims to develop efficient cell factories by rewiring cellular
metabolism. As one of the most commonly used cell factories, Saccharomyces cerevisiae …

[HTML][HTML] Review of NAD (P) H-dependent oxidoreductases: Properties, engineering and application

LS Vidal, CL Kelly, PM Mordaka, JT Heap - Biochimica et Biophysica Acta …, 2018 - Elsevier
Abstract NAD (P) H-dependent oxidoreductases catalyze the reduction or oxidation of a
substrate coupled to the oxidation or reduction, respectively, of a nicotinamide adenine …