This review highlights evidence for a role of the vagus nerve in the development of obesity
and how targeting the vagus nerve with neuromodulation or pharmacology can be used as a …

Obesity is a complex, multifactorial disease that is a major public health issue worldwide.
Currently approved anti-obesity medications and lifestyle interventions lack the efficacy and …

The vagus nerve serves as a critical connection between the central nervous system and
internal organs. Originally known for its effectiveness in treating refractory epilepsy, vagus …

Background Vagal nerve stimulation (VNS) has recently been indicated as a novel method
for treating obesity. However, the optimal stimulation parameters were unknown and …

Introduction: With the increasing prevalence of obesity and its associated comorbidities,
strides to improve treatment strategies have enhanced our understanding of the function of …

Background: The harmful consequences of non-alcoholic fatty liver disease (NAFLD) are
posing an increasing threat to public health as the incidence of diabetes and obesity …

Epigenetics encompasses the changes in gene expression triggered by environmental cues
that occur without altering the underlying DNA sequences. Although epigenetics involves a …

Deep brain stimulation (DBS) is a therapeutic option for several diseases, but its effects on
HPA axis activity and systemic inflammation are unknown. This study aimed to detect …

Vagus Nerve Stimulation (VNS) is an established palliative treatment for drug resistant
epilepsy. While effective for many patients, its mechanism of action is incompletely …

Background Weight reduction frequently occurs in patients receiving vagus nerve
stimulation (VNS) therapy. Therefore, we hypothesized that during dietary intervention for …