Systemic therapy for early-stage breast cancer: learning from the past to build the future
E Agostinetto, J Gligorov, M Piccart - Nature Reviews Clinical Oncology, 2022 - nature.com
The treatment of breast cancer has improved dramatically over the past century, from a
strictly surgical approach to a coordinated one, including local and systemic therapies …
strictly surgical approach to a coordinated one, including local and systemic therapies …
Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials
Early Breast Cancer Trialists' Collaborative Group - The Lancet, 2005 - thelancet.com
Summary Background Quinquennial overviews (1985–2000) of the randomised trials in
early breast cancer have assessed the 5 year and 10-year effects of various systemic …
early breast cancer have assessed the 5 year and 10-year effects of various systemic …
Meta-analysis of chemotherapy in head and neck cancer (MACH-NC): An update on 107 randomized trials and 19,805 patients, on behalf of MACH-NC Group
B Lacas, A Carmel, C Landais, SJ Wong… - Radiotherapy and …, 2021 - Elsevier
Abstract Background and purpose The Meta-Analysis of Chemotherapy in squamous cell
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …
Head and Neck Cancer (MACH-NC) demonstrated that concomitant chemotherapy (CT) …
ROCplot. org: Validating predictive biomarkers of chemotherapy/hormonal therapy/anti‐HER2 therapy using transcriptomic data of 3,104 breast cancer patients
Systemic therapy of breast cancer can include chemotherapy, hormonal therapy and
targeted therapy. Prognostic biomarkers are able to predict survival and predictive …
targeted therapy. Prognostic biomarkers are able to predict survival and predictive …
Axillary dissection vs no axillary dissection in women with invasive breast cancer and sentinel node metastasis: a randomized clinical trial
AE Giuliano, KK Hunt, KV Ballman, PD Beitsch… - Jama, 2011 - jamanetwork.com
Context Sentinel lymph node dissection (SLND) accurately identifies nodal metastasis of
early breast cancer, but it is not clear whether further nodal dissection affects survival …
early breast cancer, but it is not clear whether further nodal dissection affects survival …
Early discontinuation and non-adherence to adjuvant hormonal therapy are associated with increased mortality in women with breast cancer
DL Hershman, T Shao, LH Kushi, D Buono… - Breast cancer research …, 2011 - Springer
Despite the benefit of adjuvant hormonal therapy (HT) on mortality among women with
breast cancer (BC), many women are non-adherent with its use. We investigated the effects …
breast cancer (BC), many women are non-adherent with its use. We investigated the effects …
Augmented post-remission therapy for a minimal residual disease-defined high-risk subgroup of children and young people with clinical standard-risk and …
A Vora, N Goulden, C Mitchell, J Hancock… - The lancet …, 2014 - thelancet.com
Background No randomised study has shown whether stratification of treatment by minimal
residual disease (MRD) response improves outcome in children and young people with …
residual disease (MRD) response improves outcome in children and young people with …
Postoperative radiotherapy in high-risk postmenopausal breast-cancer patients given adjuvant tamoxifen: Danish Breast Cancer Cooperative Group DBCG 82c …
M Overgaard, MB Jensen, J Overgaard, PS Hansen… - The Lancet, 1999 - thelancet.com
Background Postmastectomy radiotherapy is associated with a lower locoregional
recurrence rate and improved disease-free and overall survival when combined with …
recurrence rate and improved disease-free and overall survival when combined with …
[HTML][HTML] A randomized trial of letrozole in postmenopausal women after five years of tamoxifen therapy for early-stage breast cancer
PE Goss, JN Ingle, S Martino, NJ Robert… - … England Journal of …, 2003 - Mass Medical Soc
Background In hormone-dependent breast cancer, five years of postoperative tamoxifen
therapy—but not tamoxifen therapy of longer duration—prolongs disease-free and overall …
therapy—but not tamoxifen therapy of longer duration—prolongs disease-free and overall …
Folate and ageing
RC Coombes, LS Kilburn, CF Snowdon - cancer, 2004 - thelancet.com
The FACIT trial of folic acid supple mentation in older adults by Jane Durga and colleagues
(Jan 20, p 208) 1 adds to the growing evidence of the importance of folate to the nervous …
(Jan 20, p 208) 1 adds to the growing evidence of the importance of folate to the nervous …