[HTML][HTML] Pan-retinal ganglion cell markers in mice, rats, and rhesus macaques

FM Nadal-Nicolás, C Galindo-Romero… - Zoological …, 2023 - ncbi.nlm.nih.gov
Univocal identification of retinal ganglion cells (RGCs) is an essential prerequisite for
studying their degeneration and neuroprotection. Before the advent of phenotypic markers …

Neuroprotective strategies for retinal ganglion cell degeneration: current status and challenges ahead

R Boia, N Ruzafa, ID Aires, X Pereiro… - International journal of …, 2020 - mdpi.com
The retinal ganglion cells (RGCs) are the output cells of the retina into the brain. In
mammals, these cells are not able to regenerate their axons after optic nerve injury, leaving …

Single-cell analysis of human retina identifies evolutionarily conserved and species-specific mechanisms controlling development

Y Lu, F Shiau, W Yi, S Lu, Q Wu, JD Pearson… - Developmental cell, 2020 - cell.com
The development of single-cell RNA sequencing (scRNA-seq) has allowed high-resolution
analysis of cell-type diversity and transcriptional networks controlling cell-fate specification …

Retinal ganglion cell diversity and subtype specification from human pluripotent stem cells

KB Langer, SK Ohlemacher, MJ Phillips, CM Fligor… - Stem cell reports, 2018 - cell.com
Retinal ganglion cells (RGCs) are the projection neurons of the retina and transmit visual
information to postsynaptic targets in the brain. While this function is shared among nearly …

Visual function, organization, and development of the mouse superior colliculus

J Cang, E Savier, J Barchini, X Liu - Annual review of vision …, 2018 - annualreviews.org
The superior colliculus (SC) is the most prominent visual center in mice. Studies over the
past decade have greatly advanced our understanding of the function, organization, and …

Onecut1 and Onecut2 redundantly regulate early retinal cell fates during development

D Sapkota, H Chintala, F Wu… - Proceedings of the …, 2014 - National Acad Sciences
Previously, we have shown that Onecut1 (Oc1) and Onecut2 (Oc2) are expressed in retinal
progenitor cells, developing retinal ganglion cells (RGCs), and horizontal cells (HCs) …

An excitatory amacrine cell detects object motion and provides feature-selective input to ganglion cells in the mouse retina

T Kim, F Soto, D Kerschensteiner - Elife, 2015 - elifesciences.org
Retinal circuits detect salient features of the visual world and report them to the brain
through spike trains of retinal ganglion cells. The most abundant ganglion cell type in mice …

Not a one-trick pony: Diverse connectivity and functions of the rodent lateral geniculate complex

A Monavarfeshani, U Sabbagh, MA Fox - Visual neuroscience, 2017 - cambridge.org
Often mislabeled as a simple relay of sensory information, the thalamus is a complicated
structure with diverse functions. This diversity is exemplified by roles visual thalamus plays …

[HTML][HTML] Functional assembly of accessory optic system circuitry critical for compensatory eye movements

LO Sun, CM Brady, H Cahill, T Al-Khindi, H Sakuta… - Neuron, 2015 - cell.com
Accurate motion detection requires neural circuitry that compensates for global visual field
motion. Select subtypes of retinal ganglion cells perceive image motion and connect to the …

Neurogenesis and specification of retinal ganglion cells

KT Nguyen-Ba-Charvet, A Rebsam - International journal of molecular …, 2020 - mdpi.com
Across all species, retinal ganglion cells (RGCs) are the first retinal neurons generated
during development, followed by the other retinal cell types. How are retinal progenitor cells …