Rhus coriaria L. (Sumac), a Versatile and Resourceful Food Spice with Cornucopia of Polyphenols

GES Batiha, OM Ogunyemi, HM Shaheen, FR Kutu… - Molecules, 2022 - mdpi.com
In recent years, utilization of Rhus coriaria L.(sumac) is upgrading not only in their culinary
use and human nutrition, but also in the pharmaceutical industry, food industry and …

Pregnancy and COVID-19: high or low risk of vertical transmission

HM Al-Kuraishy, AI Al-Gareeb, NKA Albezrah… - Clinical and …, 2023 - Springer
Abstract Coronavirus disease 19 (COVID-19) is an infectious disease caused by severe
acute respiratory syndrome 2 (SARS-CoV-2). Throughout the pandemic, evidence on the …

Inhibition mechanism of alpha-amylase, a diabetes target, by a steroidal pregnane and pregnane glycosides derived from Gongronema latifolium Benth

OM Ogunyemi, GA Gyebi, A Saheed, J Paul… - Frontiers in molecular …, 2022 - frontiersin.org
Alpha-amylase is widely exploited as a drug target for preventing postprandial
hyperglycemia in diabetes and other metabolic diseases. Inhibition of this enzyme by plant …

GC-MS chemical profiling, antioxidant, anti-diabetic, and anti-inflammatory activities of ethyl acetate fraction of Spilanthes filicaulis (Schumach. and Thonn.) CD …

OA Ojo, AD Ogunlakin, GA Gyebi… - Frontiers in …, 2023 - frontiersin.org
Introduction: This study aimed to investigate the chemical profile of GC-MS, antioxidant, anti-
diabetic, and anti-inflammatory activities of the ethyl acetate fraction of Spilanthes filicaulis …

[HTML][HTML] Deciphering the therapeutic role of Kigelia africana fruit in erectile dysfunction through metabolite profiling and molecular modelling

F Olawale, K Olofinsan, OM Ogunyemi… - Informatics in Medicine …, 2023 - Elsevier
Kigelia africana herbal products are often used traditionally to treat erectile dysfunction and
other sexual complaints, but the underlying mechanism is not yet understood. This study …

Discovery of genistein derivatives as potential SARS-CoV-2 main protease inhibitors by virtual screening, molecular dynamics simulations and ADMET analysis

J Liu, L Zhang, J Gao, B Zhang, X Liu, N Yang… - Frontiers in …, 2022 - frontiersin.org
Background: Due to the constant mutation of virus and the lack of specific therapeutic drugs,
the coronavirus disease 2019 (COVID-19) pandemic caused by the severe acute respiratory …

Phytochemical analysis, in vitro and in silico effects from Alstonia boonei De Wild stem bark on selected digestive enzymes and adipogenesis in 3T3-L1 preadipocytes

GO Anyanwu, UD Ejike, GA Gyebi, K Rauf… - … medicine and therapies, 2023 - Springer
Background Obesity is a global health issue arising from the unhealthy accumulation of fat.
Medicinal plants such as Alstonia boonei stem bark has been reported to possess body …

Molecular docking appraisal of Dysphania ambrosioides phytochemicals as potential inhibitor of a key triple-negative breast cancer driver gene

LO Anifowose, OK Paimo, FN Adegboyega… - In Silico …, 2023 - Springer
Triple-negative breast cancer (TNBC) is a lethal and aggressive breast cancer subtype. It is
characterized by the deficient expression of the three main receptors implicated in breast …

Discovery of novel Trichoderma-based bioactive compounds for controlling potato virus Y based on molecular docking and molecular dynamics simulation …

MN Rizk, HA Ketta, YM Shabana - Chemical and Biological Technologies …, 2024 - Springer
Background Although potato virus Y (PVY) is the most serious virus-infecting potato plants
worldwide, the losses concurred by it remain unmanageable due to the lack of efficient anti …

Identification of potential target genes of cardiac glycosides from Vernonia amygdalina Delile in HER2+ breast cancer cells

A Hermawan, D Satria, PAZ Hasibuan, F Huda… - South African Journal of …, 2024 - Elsevier
Vernonia amygdalina Delile or bitter leaf, a traditional medicinal plant endemic to Africa, has
shown anticancer properties by inhibiting the downstream signaling of human epidermal …