[HTML][HTML] Going below and beyond the surface: Microneedle structure, materials, drugs, fabrication, and applications for wound healing and tissue regeneration
Microneedle, as a novel drug delivery system, has attracted widespread attention due to its
non-invasiveness, painless and simple administration, controllable drug delivery, and …
non-invasiveness, painless and simple administration, controllable drug delivery, and …
Ocular drug delivery: present innovations and future challenges
Ocular drug delivery has always been a challenge for ophthalmologists and drug-delivery
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
scientists due to the presence of various anatomic and physiologic barriers. Inimitable static …
Design principles of microneedles for drug delivery and sampling applications
Microneedles technology is a powerful platform to achieve efficient transdermal delivery of
bioactive molecules for local or systemic therapies attributing to their minimally invasive …
bioactive molecules for local or systemic therapies attributing to their minimally invasive …
Self-implantable double-layered micro-drug-reservoirs for efficient and controlled ocular drug delivery
Eye diseases and injuries impose a significant clinical problem worldwide. Safe and
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …
effective ocular drug delivery is, however, challenging due to the presence of ocular barriers …
Recent advances of controlled drug delivery using microfluidic platforms
Conventional systematically-administered drugs distribute evenly throughout the body, get
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …
degraded and excreted rapidly while crossing many biological barriers, leaving minimum …
A facile low-dose photosensitizer-incorporated dissolving microneedles-based composite system for eliciting antitumor immunity and the abscopal effect
Q Bian, L Huang, Y Xu, R Wang, Y Gu, A Yuan, X Ma… - Acs Nano, 2021 - ACS Publications
Nanomedicine-based photodynamic therapy (PDT) for melanoma treatment has attracted
great attention. However, the complex design of polymer nanoparticles and high doses of …
great attention. However, the complex design of polymer nanoparticles and high doses of …
Strategies to develop polymeric microneedles for controlled drug release
BZ Chen, YT He, ZQ Zhao, YH Feng, L Liang… - Advanced Drug Delivery …, 2023 - Elsevier
The remarkable appeal of microneedle controlled-release systems has captivated both the
academic community and pharmaceutical industry due to their great potential for achieving …
academic community and pharmaceutical industry due to their great potential for achieving …
A rapid corneal healing microneedle for efficient ocular drug delivery
H Shi, J Zhou, Y Wang, Y Zhu, D Lin, L Lei, S Vakal… - Small, 2022 - Wiley Online Library
Fungal keratitis (FK) remains a serious clinical problem worldwide, so the ultimate goal of
the treatment is to develop a minimally invasive, safe, and effective method for ocular drug …
the treatment is to develop a minimally invasive, safe, and effective method for ocular drug …
[HTML][HTML] Intravitreal hydrogels for sustained release of therapeutic proteins
BC Ilochonwu, A Urtti, WE Hennink… - Journal of Controlled …, 2020 - Elsevier
This review highlights how hydrogel formulations can improve intravitreal protein delivery to
the posterior segment of the eye in order to increase therapeutic outcome and patient …
the posterior segment of the eye in order to increase therapeutic outcome and patient …
Ocular delivery of proteins and peptides: Challenges and novel formulation approaches
The impact of proteins and peptides on the treatment of various conditions including ocular
diseases over the past few decades has been advanced by substantial breakthroughs in …
diseases over the past few decades has been advanced by substantial breakthroughs in …