Integrated heart—coupling multiscale and multiphysics models for the simulation of the cardiac function

A Quarteroni, T Lassila, S Rossi… - Computer Methods in …, 2017 - Elsevier
Mathematical modeling of the human heart and its function can expand our understanding of
various cardiac diseases, which remain the most common cause of death in the developed …

[HTML][HTML] Biomechanical constitutive modeling of the gastrointestinal tissues: a systematic review

B Patel, A Gizzi, J Hashemi, Y Awakeem, H Gregersen… - Materials & …, 2022 - Elsevier
The gastrointestinal (GI) tract is a continuous channel through the body that consists of the
esophagus, the stomach, the small intestine, the large intestine, and the rectum. Its primary …

[HTML][HTML] A note on stress-driven anisotropic diffusion and its role in active deformable media

C Cherubini, S Filippi, A Gizzi, R Ruiz-Baier - Journal of Theoretical Biology, 2017 - Elsevier
We introduce a new model to describe diffusion processes within active deformable media.
Our general theoretical framework is based on physical and mathematical considerations …

Anisotropic stiffness and tensional homeostasis induce a natural anisotropy of volumetric growth and remodeling in soft biological tissues

FA Braeu, RC Aydin, CJ Cyron - Biomechanics and modeling in …, 2019 - Springer
Growth in soft biological tissues in general results in anisotropic changes of the tissue
geometry. It remains a key challenge in biomechanics to understand, quantify, and predict …

A curvilinear isogeometric framework for the electromechanical activation of thin muscular tissues

A Nitti, J Kiendl, A Gizzi, A Reali, MD de Tullio - Computer Methods in …, 2021 - Elsevier
We propose an isogeometric approximation of the equations describing the propagation of
an electrophysiologic stimulus over a thin cardiac tissue with the subsequent muscle …

Biological cells and coupled electro-mechanical effects: The role of organelles, microtubules, and nonlocal contributions

S Singh, JA Krishnaswamy, R Melnik - journal of the mechanical behavior …, 2020 - Elsevier
Biological cells are exposed to a variety of mechanical loads throughout their life cycles that
eventually play an important role in a wide range of cellular processes. The understanding …

A transversely isotropic thermo-hyperelastic constitutive model of myocardial tissue with a three-state cell death dynamics for cardiac radiofrequency ablation

L Molinari, L Gerardo-Giorda, A Gizzi - … of the Mechanics and Physics of …, 2022 - Elsevier
Constitutive models of radiofrequency catheter ablation (RFCA) lack a reliable three-
dimensional microstructural representation of the myocardium. Besides, complex …

Evolution of fiber distributions in homogenized constrained mixture models of soft tissue growth and remodeling: Uniaxial loading

A Gizzi, CJ Cyron, C Falcinelli, M Vasta - … of the Mechanics and Physics of …, 2024 - Elsevier
Growth and remodeling in soft tissue changes, in general, the orientation distribution of the
collagen fibers in the tissue. So far, the governing principles are still incompletely …

Competing mechanisms of stress-assisted diffusivity and stretch-activated currents in cardiac electromechanics

A Loppini, A Gizzi, R Ruiz-Baier, C Cherubini… - Frontiers in …, 2018 - frontiersin.org
We numerically investigate the role of mechanical stress in modifying the conductivity
properties of cardiac tissue, and also assess the impact of these effects in the solutions …

Modeling of electrodynamic processes by means of mechanical analogies

EA Ivanova - ZAMM‐Journal of Applied Mathematics and …, 2021 - Wiley Online Library
This study continues the line of earlier research in mechanical models of electrodynamic
processes suggested in previous works. The basic steps we take to construct these models …