Only humans have human placentas: molecular differences between mice and humans

A Schmidt, DM Morales-Prieto, J Pastuschek… - Journal of reproductive …, 2015 - Elsevier
The placenta is one of the organs with the highest evolutionary diversity among animal
species. In consequence, an animal model that reflects human placentation exactly does not …

Predicting tumor response to drugs based on gene-expression biomarkers of sensitivity learned from cancer cell lines

Y Li, DM Umbach, JM Krahn, I Shats, X Li, L Li - BMC genomics, 2021 - Springer
Background Human cancer cell line profiling and drug sensitivity studies provide valuable
information about the therapeutic potential of drugs and their possible mechanisms of action …

IMUP and GPRC5A: two newly identified risk score indicators in pancreatic ductal adenocarcinoma

R Wei, G Qi, Z Zeng, N Shen, Z Wang, H Shen… - Cancer cell …, 2021 - Springer
Background Pancreatic cancer has been a threateningly lethal malignant tumor worldwide.
Despite the promising survival improvement in other cancer types attributing to the fast …

Human-specific protein isoforms produced by novel splice sites in the human genome after the human-chimpanzee divergence

DS Kim, Y Hahn - BMC bioinformatics, 2012 - Springer
Background Evolution of splice sites is a well-known phenomenon that results in transcript
diversity during human evolution. Many novel splice sites are derived from repetitive …

Downregulation of immortalization-upregulated protein suppresses the progression of breast cancer cell lines by regulating epithelial–mesenchymal transition

J Wen, L Lin, B Lin, E Xia, J Qu… - Cancer Management and …, 2020 - Taylor & Francis
Introduction Breast cancer (BC) is one of the most prevalent malignancies in women and its
incidence has increased steadily over recent years (0.3% per year). However, the …

Immortalization up‐regulated protein promotes tumorigenesis and inhibits apoptosis of papillary thyroid cancer

L Lin, J Wen, B Lin, A Bhandari, D Zheng… - Journal of Cellular …, 2020 - Wiley Online Library
The incidence of thyroid cancer is increasing in recent years worldwide, but the underlying
mechanisms await further exploration. We utilized the bioinformatic analysis to discover that …

Etude des intéractions protéine-protéine par double hybride bactérien: applications en agro-alimentaire et en santé.

ML Gervais - 2010 - theses.hal.science
Les interactions entre protéines sont un enjeu majeur en recherche. Hautement spécifiques,
elles régulent l'organisation cellulaire, ainsi que les réponses aux stimuli extérieurs; ce sont …

[HTML][HTML] Effect of Immortalization-Upregulated Protein-2 (IMUP-2) on Cell Death of Trophoblast

R Jung, JH Choi, HJ Lee, JK Kim… - Development & …, 2013 - ncbi.nlm.nih.gov
Trophoblasts, in the placenta, play a role for placental development as well as implantation
in the early pregnancy. The characteristics and functions of trophoblast are identified by their …

[引用][C] Effect of Immortalization-Upregulated Protein-2 (IMUP-2) on Cell Death of Trophoblast Ran Jung, Jong Ho Choi", Hyun Jung Lee", Jin Kyeoung Kim'and'Gi Jin …

R Jung