Transgenerational inheritance: how impacts to the epigenetic and genetic information of parents affect offspring health

MJ Xavier, SD Roman, RJ Aitken… - Human reproduction …, 2019 - academic.oup.com
BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

How deep are the roots of economic development?

E Spolaore, R Wacziarg - Journal of economic literature, 2013 - aeaweb.org
The empirical literature on economic growth and development has moved from the study of
proximate determinants to the analysis of ever deeper, more fundamental factors, rooted in …

Molecular insights into transgenerational non-genetic inheritance of acquired behaviours

J Bohacek, IM Mansuy - Nature Reviews Genetics, 2015 - nature.com
Behavioural traits in mammals are influenced by environmental factors, which can interact
with the genome and modulate its activity by complex molecular interplay. Environmental …

Intergenerational influences on child growth and undernutrition

R Martorell, A Zongrone - Paediatric and perinatal …, 2012 - Wiley Online Library
Intergenerational effects on linear growth are well documented. Several generations are
necessary in animal models to 'wash out'effects of undernutrition, consistent with the …

Exploring the biological contributions to human health: does sex matter?

ML Pardue, TM Wizemann - 2001 - books.google.com
It's obvious why only men develop prostate cancer and why only women get ovarian cancer.
But it is not obvious why women are more likely to recover language ability after a stroke …

The developmental origins of adult disease (Barker) hypothesis

HA De Boo, JE Harding - Australian and New Zealand Journal …, 2006 - Wiley Online Library
Many studies have provided evidence for the hypothesis that size at birth is related to the
risk of developing disease in later life. In particular, links are well established between …

Recent progress in epigenetics of obesity

FY Wu, RX Yin - Diabetology & Metabolic Syndrome, 2022 - Springer
Nowadays, obesity is one of the largest public health problems worldwide. In the last few
decades, there has been a marked increase in the obesity epidemic and its related …

Prenatal famine and adult health

LH Lumey, AD Stein, E Susser - Annual review of public health, 2011 - annualreviews.org
We review human studies on the relation between acute exposures to prenatal famine and
adult physical and mental health. These studies are observational and include exposures to …

Transgenerational epigenetic effects

NA Youngson, E Whitelaw - Annu. Rev. Genomics Hum. Genet., 2008 - annualreviews.org
Transgenerational epigenetic effects include all processes that have evolved to achieve the
nongenetic determination of phenotype. There has been a long-standing interest in this area …

Biology as destiny? Short-and long-run determinants of intergenerational transmission of birth weight

J Currie, E Moretti - Journal of Labor economics, 2007 - journals.uchicago.edu
We use a unique data set of California births to ask whether intergenerational correlations in
health contribute to the perpetuation of economic status. We find that if a mother was low …